Search
Now showing items 1-3 of 3
Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.
(Scientific reports, 2015-01)
Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway
may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1
and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population.
(Oncotarget, 2015-12)
Published data on the association between PRKAA1 rs13361707 T > C polymorphism and
gastric cancer (GCa) susceptibility were inconclusive. To derive a more precise estimation
of the association, we conducted a large-scale ...
Genetic Variants of the MDM2 Gene Are Predictive of Treatment-Related Toxicities and Overall Survival in Patients With Advanced NSCLC.
(Clin Lung Cancer, 2015-09)
INTRODUCTION: Platinum agents can cause the formation of DNA adducts and induce apoptosis
to eliminate tumor cells. The aim of the present study was to investigate the influence
of genetic variants of MDM2 on chemotherapy-related ...