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A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania.

Bartlett, John A; Chow, S-C; Crump, John Andrew; Cunningham, Coleen; Hamilton, Carol; Kibiki, Gibson S; Lancaster, KE; ... (18 authors) (BMC Infect Dis, 2014-02-20)

BACKGROUND: Routine tuberculosis culture remains unavailable in many high-burden areas, including Tanzania. This study sought to determine the impact of providing mycobacterial culture results over standard of care ...

Performance of nucleic acid amplification following extraction of 5 milliliters of whole blood for diagnosis of Mycobacterium tuberculosis bacteremia.

Crump, John Andrew; Maro, Venance P; Morrissey, AB; Njau, Boniface N; Procop, GW; Ramadhani, HO; Reller, LB; ... (8 authors) (J Clin Microbiol, 2012-01)

To investigate the performance of a nucleic acid amplification test (NAAT) for the diagnosis of Mycobacterium tuberculosis bacteremia, 5-ml aliquots of blood were inoculated into bioMérieux mycobacterial (MB) bottles and ...

Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.

Bartlett, John A; Chow, S-C; Crump, John Andrew; Maro, Venance P; Morrissey, AB; Mushi, GS; Mwako, MS; ... (12 authors) (Clin Infect Dis, 2012-07)

BACKGROUND: Disseminated tuberculosis is a major health problem in countries where generalized human immunodeficiency virus (HIV) infection epidemics coincide with high tuberculosis incidence rates; data are limited on patient ...

Brucellosis among hospitalized febrile patients in northern Tanzania.

Afwamba, IA; Bartlett, John A; Biggs, HM; Bouley, AJ; Cleaveland, S; Crump, John Andrew; Kinabo, GD; ... (11 authors) (Am J Trop Med Hyg, 2012-12)

Acute and convalescent serum samples were collected from febrile inpatients identified at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive blood culture or a ≥ 4-fold increase in ...

Leptospirosis and human immunodeficiency virus co-infection among febrile inpatients in northern Tanzania.

Biggs, HM; Bui, DM; Crump, John Andrew; Galloway, RL; Maro, Venance P; Morrissey, AB (Vector Borne Zoonotic Dis, 2013-08)

BACKGROUND: Leptospirosis and human immunodeficiency virus (HIV) infection are prevalent in many areas, including northern Tanzania, yet little is known about their interaction. METHODS: We enrolled febrile inpatients at ...

Leptospirosis among hospitalized febrile patients in northern Tanzania.

Bartlett, John A; Biggs, HM; Bui, DM; Crump, John Andrew; Galloway, RL; Kinabo, GD; Maro, Venance P; ... (12 authors) (Am J Trop Med Hyg, 2011-08)

We enrolled consecutive febrile admissions to two hospitals in Moshi, Tanzania. Confirmed leptospirosis was defined as a ≥ 4-fold increase in microscopic agglutination test (MAT) titer; probable leptospirosis as reciprocal ...

Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study.

Bartlett, John A; Crump, John Andrew; Galloway, RL; Kinabo, GD; Maro, Venance P; Massung, RF; Morrissey, AB; ... (12 authors) (PLoS Negl Trop Dis, 2013)

INTRODUCTION: The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner. In many areas, ...

Chikungunya and dengue fever among hospitalized febrile patients in northern Tanzania.

Bartlett, John A; Chow, A; Crump, John Andrew; Gubler, DJ; Hertz, JT; Howe, S; Kinabo, GD; ... (14 authors) (Am J Trop Med Hyg, 2012-01)

Consecutive febrile admissions were enrolled at two hospitals in Moshi, Tanzania. Confirmed acute Chikungunya virus (CHIKV), Dengue virus (DENV), and flavivirus infection were defined as a positive polymerase chain reaction ...