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Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.

Abrahams, BS; Alvarez Retuerto, AI; Bradfield, JP; Bucan, M; Buxbaum, JD; Cantor, RM; Cook, EH; ... (36 authors) (PLoS Genet, 2009-06)

The genetics underlying the autism spectrum disorders (ASDs) is complex and remains poorly understood. Previous work has demonstrated an important role for structural variation in a subset of cases, but has lacked the resolution ...

Diesel exhaust particles activate the matrix-metalloproteinase-1 gene in human bronchial epithelia in a beta-arrestin-dependent manner via activation of RAS.

Brinckerhoff, CE; Cho, SH; Ghio, Andrew J; Li, J; Liedtke, Wolfgang Bernhard; Simon, SA (Environ Health Perspect, 2009-03)

BACKGROUND: Diesel exhaust particles (DEPs) are globally relevant air pollutants that exert a detrimental human health impact. However, mechanisms of damage by DEP exposure to human respiratory health and human susceptibility ...

Using functional magnetic resonance imaging in psychotherapy research: a brief introduction to concepts, methods, and task selection.

Carrig, Madeline; Kolden, GG; Strauman, Timothy J (Psychother Res, 2009-07)

Functional magnetic resonance imaging (fMRI) has become an increasingly important methodology in the study of psychotherapy outcome and process. In this article, the authors offer a brief introduction to the use of fMRI ...

Substance abuse, treatment needs and access among female sex workers and non-sex workers in Pretoria, South Africa.

Wechsberg, WM; Wu, L-T; Zule, WA; Parry, CD; Browne, FA; Luseno, WK; Kline, T; ... (8 authors) (Subst Abuse Treat Prev Policy, 2009-05-27)

BACKGROUND: This study examined cross-sectional data collected from substance-using female sex workers (FSW) and non-sex workers (non-SW) in Pretoria, South Africa, who entered a randomized controlled trial. METHODS: Women ...

Dominance, politics, and physiology: voters' testosterone changes on the night of the 2008 United States presidential election.

Beehner, JC; Kuhn, CM; LaBar, Kevin S; Saini, EK; Stanton, SJ (PLoS One, 2009-10-21)

BACKGROUND: Political elections are dominance competitions. When men win a dominance competition, their testosterone levels rise or remain stable to resist a circadian decline; and when they lose, their testosterone levels ...

The toxicology of climate change: environmental contaminants in a warming world.

Clark, BW; Erwin, KN; Levin, Edward Daniel; McElwee, MK; Miller, HD; Noyes, PD; Van Tiem, LA; ... (8 authors) (Environ Int, 2009-08)

Climate change induced by anthropogenic warming of the earth's atmosphere is a daunting problem. This review examines one of the consequences of climate change that has only recently attracted attention: namely, the effects ...

Resolving response, decision, and strategic control: evidence for a functional topography in dorsomedial prefrontal cortex.

Huettel, Scott; Rosati, Alexandra G; Taren, AA; Venkatraman, V (J Neurosci, 2009-10-21)

The dorsomedial prefrontal cortex (DMPFC) plays a central role in aspects of cognitive control and decision making. Here, we provide evidence for an anterior-to-posterior topography within the DMPFC using tasks that evoke ...

Common genetic variation and the control of HIV-1 in humans.

Antonarakis, SE; Beckmann, JS; Carrington, Mary; Castagna, A; Cirulli Rogers, Elizabeth T; Colombo, S; Cozzi-Lepri, A; ... (38 authors) (PLoS Genet, 2009-12)

To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants ...