Now showing items 1-10 of 61
The role of lipid-related genes, aging-related processes, and environment in healthspan.
(Aging Cell, 2013-04)
The inherent complexity of aging-related traits can temper progress in unraveling the genetic origins of healthspan. We focus on two generations in the Framingham Heart Study, the original (FHS) and offspring (FHSO) cohorts, ...
Educational interventions to improve recognition of delirium: a systematic review.
(J Am Geriatr Soc, 2013-11)
Delirium is a common and serious condition that is underrecognized in older adults in a variety of healthcare settings. It is poorly recognized because of deficiencies in provider knowledge and its atypical presentation. ...
Validity of low-intensity continuous renal replacement therapy*.
(Critical care medicine, 2013-11)
OBJECTIVE: To study the hospital mortality of patients with severe acute kidney injury treated with low-intensity continuous renal replacement therapy. DESIGN: Multicenter retrospective observational study (Japanese Society ...
Food, class, and health: the role of the perceived body in the social reproduction of health.
(Health communication, 2013-05)
The association between social class and cardiovascular health is complex, involving a constant interplay of factors as individuals integrate external information from the media, health care providers, and people they know ...
Driving while aging: a global instrumental activity for the 21st century.
(J Gerontol A Biol Sci Med Sci, 2013-05)
Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population.
(PloS one, 2013-01)
BACKGROUND: The mTOR gene regulates cell growth by controlling mRNA translation, ribosome biogenesis, autophagy, and metabolism. Abnormally increased expression of mTOR was associated with carcinogenesis, and its functional ...
Polymorphisms of nucleotide excision repair genes predict melanoma survival.
(The Journal of investigative dermatology, 2013-07)
Melanoma is the most highly malignant skin cancer, and nucleotide excision repair (NER) is involved in melanoma susceptibility. In this analysis of 1,042 melanoma patients, we evaluated whether genetic variants of NER genes ...
A latent factor linear mixed model for high-dimensional longitudinal data analysis.
(Statistics in medicine, 2013-10)
High-dimensional longitudinal data involving latent variables such as depression and anxiety that cannot be quantified directly are often encountered in biomedical and social sciences. Multiple responses are used to characterize ...
The AOSpine North America Geriatric Odontoid Fracture Mortality Study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up.
STUDY DESIGN: Retrospective, multicenter cohort study. OBJECTIVE: Assess for differences in short- and long-term mortality between operative and nonoperative treatment for elderly patients with type II odontoid fractures. ...
Chikungunya as a cause of acute febrile illness in southern Sri Lanka.
(PLoS One, 2013)
BACKGROUND: Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a 40-year hiatus. We sought to identify and characterize acute chikungunya infection (CHIK) in patients presenting with acute undifferentiated ...