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Mitochondrial mutations in adenoid cystic carcinoma of the salivary glands.
(PLoS One, 2009-12-30)
BACKGROUND: The MitoChip v2.0 resequencing array is an array-based technique allowing
for accurate and complete sequencing of the mitochondrial genome. No studies have
investigated mitochondrial mutation in salivary gland ...
Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection.
(PLoS Med, 2009-07-07)
BACKGROUND: The antibody response to HIV-1 does not appear in the plasma until approximately
2-5 weeks after transmission, and neutralizing antibodies to autologous HIV-1 generally
do not become detectable until 12 weeks ...
Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.
(PLoS Genet, 2009-06)
The genetics underlying the autism spectrum disorders (ASDs) is complex and remains
poorly understood. Previous work has demonstrated an important role for structural
variation in a subset of cases, but has lacked the resolution ...
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
(Pain Med, 2008-11)
BACKGROUND: The aim of this report is to determine the frequency of aberrant drug
behaviors and their relationship to substance abuse disorders in a large primary sample
of patients receiving opioids for chronic pain. METHODS: ...
The design of an observational study of hypertension management, adherence and pressure control in Blood Pressure Success Zone Program participants.
(Int J Clin Pract, 2008-09)
AIMS: The Blood Pressure Success Zone (BPSZ) Program, a nationwide initiative, provides
education in addition to a complimentary trial of one of three antihypertensive medications.
The BPSZ Longitudinal Observational Study ...