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Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages.
(Arthritis Res Ther, 2009)
INTRODUCTION: Certain amino acids within proteins have been reported to change from
the L form to the D form over time. This process is known as racemization and is most
likely to occur in long-lived low-turnover tissues ...
Comorbidity, age, race and stage at diagnosis in colorectal cancer: a retrospective, parallel analysis of two health systems.
(BMC Cancer, 2008-11-25)
BACKGROUND: Stage at diagnosis plays a significant role in colorectal cancer (CRC)
survival. Understanding which factors contribute to a more advanced stage at diagnosis
is vital to improving overall survival. Comorbidity, ...
Age-specific differences in oncogenic pathway deregulation seen in human breast tumors.
(PLoS One, 2008-01-02)
PURPOSE: To define the biology driving the aggressive nature of breast cancer arising
in young women. EXPERIMENTAL DESIGN: Among 784 patients with early stage breast cancer,
using prospectively-defined, age-specific cohorts ...