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Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck.
(BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase
family plays crucial roles in carcinogenesis and progression of several cancers, including
squamous cell carcinoma of the head and neck ...
Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms.
(Breast Cancer Res Treat, 2011-07)
The observed bimodal patterns of breast cancer incidence in the U.S. suggested that
breast cancer may be viewed as more than one biological entity. We studied the factors
potentially contributing to this phenomenon, specifically ...
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
(PLoS genetics, 2011-03-17)
Genome-wide association studies (GWAS) have been successful in identifying common
genetic variation involved in susceptibility to etiologically complex disease. We
conducted a GWAS to identify common genetic variation involved ...