Search
Now showing items 1-10 of 11
Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck.
(BMC cancer, 2011-06-20)
Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase
family plays crucial roles in carcinogenesis and progression of several cancers, including
squamous cell carcinoma of the head and neck ...
HPV16 antibodies as risk factors for oropharyngeal cancer and their association with tumor HPV and smoking status.
(Oral Oncol, 2015-07)
BACKGROUND: Antibodies (Abs) to the HPV16 proteome increase risk for HPV-associated
OPC (HPVOPC). The goal of this study was to investigate the association of a panel
of HPV16 Abs with risk for OPC as well as the association ...
Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence.
(Prostate Cancer Prostatic Dis, 2015-12)
BACKGROUND: Telomere-related genes play an important role in carcinogenesis and progression
of prostate cancer (PCa). It is not fully understood whether genetic variations in
telomere-related genes are associated with development ...
Relationship Between Cancer and Cardiovascular Outcomes Following Percutaneous Coronary Intervention.
(J Am Heart Assoc, 2015-07-06)
BACKGROUND: Cardiovascular disease and cancer increasingly coexist, yet relationships
between cancer and long-term cardiovascular outcomes post-percutaneous coronary intervention
(PCI) are not well studied. METHODS AND RESULTS: ...
Polymorphisms in the AKT1 and AKT2 genes and oesophageal squamous cell carcinoma risk in an Eastern Chinese population.
(Journal of cellular and molecular medicine, 2016-04)
Ethnic Han Chinese are at high risk of developing oesophageal squamous cell carcinoma
(ESCC). Aberrant activation of the AKT signalling pathway is involved in many cancers,
including ESCC. Some single nucleotide polymorphisms ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...
Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.
(Oncotarget, 2016-05)
The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated
cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially
functional single nucleotide ...
Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations.
(Oncotarget, 2017-04)
Genetic variants of nucleotide excision repair (NER) genes have been extensively investigated
for their roles in the development of prostate cancer (PCa); however, the published
results have been inconsistent. In a hospital-based ...
Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.
(PloS one, 2012-01)
BACKGROUND: Excision repair cross complementing group 5 (ERCC5 or XPG) plays an important
role in regulating DNA excision repair; its functional single nucleotide polymorphisms
(SNPs) may alter DNA repair capacity and thus ...
A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.
(Scientific reports, 2016-01-28)
AKT is an important signal transduction protein that plays a crucial role in cancer
development. Therefore, we evaluated associations between single nucleotide polymorphisms
(SNPs) in the AKT promoter region and gastric ...