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    Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. 

    Fong, AM; Lefkowitz, Robert J; Patel, DD; Premont, Richard Thomas; Richardson, RM; Yu, Y-RA (Proc Natl Acad Sci U S A, 2002-05-28)
    Lymphocyte chemotaxis is a complex process by which cells move within tissues and across barriers such as vascular endothelium and is usually stimulated by chemokines such as stromal cell-derived factor-1 (CXCL12) acting ...
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    Beta-arrestin-2 regulates the development of allergic asthma. 

    Fong, AM; Lawson, BL; Lefkowitz, Robert J; Patel, DD; Savov, JD; Schwartz, David A; Walker, JKL (J Clin Invest, 2003-08)
    Asthma is a chronic inflammatory disorder of the airways that is coordinated by Th2 cells in both human asthmatics and animal models of allergic asthma. Migration of Th2 cells to the lung is key to their inflammatory function ...
     

     

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    AuthorFong, AM (2)
    Lefkowitz, Robert J (2)
    Patel, DD (2)
    Lawson, BL (1)Premont, Richard Thomas (1)Richardson, RM (1)Savov, JD (1)Schwartz, David A (1)Walker, JKL (1)Yu, Y-RA (1)Date Issued2002 (1)2003 (1)TypeJournal article (2)SubjectAnimals (2)
    Arrestins (2)
    beta-Arrestins (2)Lymphocytes (2)Mice (2)Mice, Inbred C57BL (2)Antigens, CD3 (1)Antigens, CD4 (1)Asthma (1)beta-Arrestin 2 (1)... View MoreAffiliation of Duke Author(s)Basic Science Departments (2)Biochemistry (2)Chemistry (2)
    Clinical Science Departments (2)
    Duke (2)Duke Cancer Institute (2)Institutes and Centers (2)Medicine (2)Medicine, Cardiology (2)Pathology (2)... View More