Search
Now showing items 1-10 of 42
The pallial basal ganglia pathway modulates the behaviorally driven gene expression of the motor pathway.
(Eur J Neurosci, 2007-04)
The discrete neural network for songbird vocal communication provides an effective
system to study neural mechanisms of learned motor behaviors in vertebrates. This
system consists of two pathways--a vocal motor pathway ...
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
(Science (New York, N.Y.), 2005-02)
Most protein phosphatases have little intrinsic substrate specificity, making selective
pharmacological inhibition of specific dephosphorylation reactions a challenging problem.
In a screen for small molecules that protect ...
A fruit in the hand or two in the bush? Divergent risk preferences in chimpanzees and bonobos.
(Biol Lett, 2008-06-23)
Human and non-human animals tend to avoid risky prospects. If such patterns of economic
choice are adaptive, risk preferences should reflect the typical decision-making environments
faced by organisms. However, this approach ...
Intracoronary adenovirus-mediated delivery and overexpression of the beta(2)-adrenergic receptor in the heart : prospects for molecular ventricular assistance.
(Circulation, 2000-02-01)
BACKGROUND: Genetic modulation of ventricular function may offer a novel therapeutic
strategy for patients with congestive heart failure. Myocardial overexpression of
beta(2)-adrenergic receptors (beta(2)ARs) has been shown ...
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
(PLoS One, 2008-04-02)
BACKGROUND: Previous work has demonstrated the potential for peripheral blood (PB)
gene expression profiling for the detection of disease or environmental exposures.
METHODS AND FINDINGS: We have sought to determine the ...
FoxP2 expression in avian vocal learners and non-learners.
(J Neurosci, 2004-03-31)
Most vertebrates communicate acoustically, but few, among them humans, dolphins and
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene
linked to human speech and has been the target of positive ...
Enhanced rewarding properties of morphine, but not cocaine, in beta(arrestin)-2 knock-out mice.
(J Neurosci, 2003-11-12)
The reinforcing and psychomotor effects of morphine involve opiate stimulation of
the dopaminergic system via activation of mu-opioid receptors (muOR). Both mu-opioid
and dopamine receptors are members of the G-protein-coupled ...
Molecular mapping of brain areas involved in parrot vocal communication.
(J Comp Neurol, 2000-03-27)
Auditory and vocal regulation of gene expression occurs in separate discrete regions
of the songbird brain. Here we demonstrate that regulated gene expression also occurs
during vocal communication in a parrot, belonging ...
A relationship between behavior, neurotrophin expression, and new neuron survival.
(Proc Natl Acad Sci U S A, 2000-07-18)
The high vocal center (HVC) controls song production in songbirds and sends a projection
to the robust nucleus of the archistriatum (RA) of the descending vocal pathway. HVC
receives new neurons in adulthood. Most of the ...
Differential expression of glutamate receptors in avian neural pathways for learned vocalization.
(J Comp Neurol, 2004-08-09)
Learned vocalization, the substrate for human language, is a rare trait. It is found
in three distantly related groups of birds-parrots, hummingbirds, and songbirds. These
three groups contain cerebral vocal nuclei for learned ...