Search
Now showing items 1-10 of 105
Pathogenesis of growth failure and partial reversal with gene therapy in murine and canine Glycogen Storage Disease type Ia.
(Mol Genet Metab, 2013-06)
Glycogen Storage Disease type Ia (GSD-Ia) in humans frequently causes delayed bone
maturation, decrease in final adult height, and decreased growth velocity. This study
evaluates the pathogenesis of growth failure and the ...
Body temperature and thermal environment in a generalized arboreal anthropoid, wild mantled howling monkeys (Alouatta palliata).
(Am J Phys Anthropol, 2014-05)
Free-ranging primates are confronted with the challenge of maintaining an optimal
range of body temperatures within a thermally dynamic environment that changes daily,
seasonally, and annually. While many laboratory studies ...
Comparative genomics reveals insights into avian genome evolution and adaptation.
(Science, 2014-12-12)
Birds are the most species-rich class of tetrapod vertebrates and have wide relevance
across many research fields. We explored bird macroevolution using full genomes from
48 avian species representing all major extant clades. ...
MRP3: a molecular target for human glioblastoma multiforme immunotherapy.
(BMC Cancer, 2010-09-01)
BACKGROUND: Glioblastoma multiforme (GBM) is refractory to conventional therapies.
To overcome the problem of heterogeneity, more brain tumor markers are required for
prognosis and targeted therapy. We have identified and ...
A fruit in the hand or two in the bush? Divergent risk preferences in chimpanzees and bonobos.
(Biol Lett, 2008-06-23)
Human and non-human animals tend to avoid risky prospects. If such patterns of economic
choice are adaptive, risk preferences should reflect the typical decision-making environments
faced by organisms. However, this approach ...
Differences in the cognitive skills of bonobos and chimpanzees.
(PLoS One, 2010-08-27)
While bonobos and chimpanzees are both genetically and behaviorally very similar,
they also differ in significant ways. Bonobos are more cautious and socially tolerant
while chimpanzees are more dependent on extractive foraging, ...
Gene expression signatures of radiation response are specific, durable and accurate in mice and humans.
(PLoS One, 2008-04-02)
BACKGROUND: Previous work has demonstrated the potential for peripheral blood (PB)
gene expression profiling for the detection of disease or environmental exposures.
METHODS AND FINDINGS: We have sought to determine the ...
Intraspecific variation in semicircular canal morphology-A missing element in adaptive scenarios?
(American journal of physical anthropology, 2019-01)
OBJECTIVES:Recent evidence suggests that the amount of intraspecific variation in
semicircular canal morphology may, itself, be evidence for varying levels of selection
related to locomotor demands. To determine the extent ...
The temporal spectrum of adult mosquito population fluctuations: conceptual and modeling implications.
(PLoS One, 2014)
An improved understanding of mosquito population dynamics under natural environmental
forcing requires adequate field observations spanning the full range of temporal scales
over which mosquito abundance fluctuates in natural ...
Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings.
(J Neurosci, 2015-03-18)
This study combines for the first time two major approaches to understanding the function
and structure of neural circuits: large-scale multielectrode recordings, and confocal
imaging of labeled neurons. To achieve this ...