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Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.

Steinberg, Benjamin A; Holmes, Dajuanicia N; Piccini, Jonathan P; Ansell, Jack; Chang, Paul; Fonarow, Gregg C; Gersh, Bernard; ... (15 authors) (J Am Heart Assoc, 2013-11-25)

BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis in atrial fibrillation. Adoption patterns of this new agent in community practice are unknown. METHODS AND RESULTS: We studied patterns ...

A risk score for in-hospital death in patients admitted with ischemic or hemorrhagic stroke.

Smith, Eric E; Shobha, Nandavar; Dai, David; Olson, DaiWai M; Reeves, Mathew J; Saver, Jeffrey L; Hernandez, Adrian F; ... (10 authors) (J Am Heart Assoc, 2013-01-28)

BACKGROUND: We aimed to derive and validate a single risk score for predicting death from ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH). METHODS AND RESULTS: Data from 333 865 stroke ...

Trends in anemia management in US hemodialysis patients 2004-2010.

Miskulin, Dana C; Zhou, Jing; Tangri, Navdeep; Bandeen-Roche, Karen; Cook, Courtney; Ephraim, Patti L; Crews, Deidra C; ... (13 authors) (BMC Nephrol, 2013-12-01)

BACKGROUND: There have been major changes in the management of anemia in US hemodialysis patients in recent years. We sought to determine the influence of clinical trial results, safety regulations, and changes in reimbursement ...

Embolization of patent foramen ovale closure devices: incidence, role of imaging in identification, potential causes, and management.

Goel, Sachin S; Aksoy, Olcay; Tuzcu, E Murat; Krasuski, Richard A; Kapadia, Samir R (Tex Heart Inst J, 2013)

Transcatheter patent foramen ovale (PFO) closure is an alternative to antiplatelet or anticoagulative therapy in patients with cryptogenic stroke, and it is associated with a small incidence of periprocedural sequelae. Because ...

Racial differences in the prevalence and outcomes of atrial fibrillation among patients hospitalized with heart failure.

Thomas, Kevin L; Piccini, Jonathan P; Liang, Li; Fonarow, Gregg C; Yancy, Clyde W; Peterson, Eric D; Hernandez, Adrian F; ... (8 authors) (J Am Heart Assoc, 2013-09-26)

BACKGROUND: The intersection of heart failure (HF) and atrial fibrillation (AF) is common, but the burden of AF among black patients with HF is poorly characterized. We sought to determine the prevalence of AF, characteristics, ...

Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.

Watkins, Lana L; Koch, Gary G; Sherwood, Andrew; Blumenthal, James A; Davidson, Jonathan RT; O'Connor, Christopher; Sketch, Michael H (J Am Heart Assoc, 2013-03-19)

BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD) patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence of depression and anxiety. We examined whether ...