Search
Now showing items 1-10 of 22
Hypertension and obesity as cardiovascular risk factors among HIV seropositive patients in Western Kenya.
(PLoS One, 2011)
BACKGROUND: There is increased risk of cardiovascular disease among HIV seropositive
individuals. The prevalence of HIV is highest in sub-Saharan Africa; however, HIV-related
cardiovascular risk research is largely derived ...
Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.
(BMC Nephrol, 2012-12-06)
BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about
many common treatment strategies for patients with end stage renal disease (ESRD).
METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...
Relief and Recurrence of Congestion During and After Hospitalization for Acute Heart Failure: Insights From Diuretic Optimization Strategy Evaluation in Acute Decompensated Heart Failure (DOSE-AHF) and Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARESS-HF).
(Circ Heart Fail, 2015-07)
BACKGROUND: Congestion is the most frequent cause for hospitalization in acute decompensated
heart failure. Although decongestion is a major goal of acute therapy, it is unclear
how the clinical components of congestion ...
Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence.
(Prostate Cancer Prostatic Dis, 2015-12)
BACKGROUND: Telomere-related genes play an important role in carcinogenesis and progression
of prostate cancer (PCa). It is not fully understood whether genetic variations in
telomere-related genes are associated with development ...
Contemporary trends and predictors of postacute service use and routine discharge home after stroke.
(J Am Heart Assoc, 2015-02-23)
BACKGROUND: Returning home after the hospital is a primary aim for healthcare; however,
additional postacute care (PAC) services are sometimes necessary for returning stroke
patients to their pre-event status. Recent trends ...
The ORBIT bleeding score: a simple bedside score to assess bleeding risk in atrial fibrillation.
(Eur Heart J, 2015-12-07)
BACKGROUND: Therapeutic decisions in atrial fibrillation (AF) are often influenced
by assessment of bleeding risk. However, existing bleeding risk scores have limitations.
OBJECTIVES: We sought to develop and validate a ...
Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study.
(BMC Public Health, 2012-06-21)
BACKGROUND: Treatment of latent tuberculosis infection (LTBI) is a key component in
U.S. tuberculosis control, assisted by recent improvements in LTBI diagnostics and
therapeutic regimens. Effectiveness of LTBI therapy, ...
Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population.
(Oncotarget, 2016-05)
The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated
cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially
functional single nucleotide ...
Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations.
(PloS one, 2014-01)
MicroRNAs are a new class of small non-protein-coding RNAs that sometimes function
as tumor suppressors or oncogenes. Aberrant expression and structural alteration of
microRNAs have been reported to be involved in tumorigenesis ...
Early adoption of dabigatran and its dosing in US patients with atrial fibrillation: results from the outcomes registry for better informed treatment of atrial fibrillation.
(J Am Heart Assoc, 2013-11-25)
BACKGROUND: Dabigatran is a novel oral anticoagulant approved for thromboprophylaxis
in atrial fibrillation. Adoption patterns of this new agent in community practice
are unknown. METHODS AND RESULTS: We studied patterns ...