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Human longevity and variation in GH/IGF-1/insulin signaling, DNA damage signaling and repair and pro/antioxidant pathway genes: cross sectional and longitudinal studies.
(Exp Gerontol, 2012-05)
Here we explore association with human longevity of common genetic variation in three
major candidate pathways: GH/IGF-1/insulin signaling, DNA damage signaling and repair
and pro/antioxidants by investigating 1273 tagging ...
Prevalence, components, and correlates of metabolic syndrome (MetS) among elderly Muscovites.
(Arch Gerontol Geriatr, 2012-09)
The goal of this study is to estimate the prevalence of MetS, together with its components
and correlates, among elderly Russians. Our population-based sample included randomly
selected residents of Moscow aged 55 and older: ...
Cancer and longevity--is there a trade-off? A study of cooccurrence in Danish twin pairs born 1900-1918.
(J Gerontol A Biol Sci Med Sci, 2012-05)
BACKGROUND: Animal models and a few human studies have suggested a complex interaction
between cancer risk and longevity indicating a trade-off where low cancer risk is
associated with accelerating aging phenotypes and, ...