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Clinical characteristics and 12-month outcomes of patients with valvular and non-valvular atrial fibrillation in Kenya.
(PLoS One, 2017)
BACKGROUND: Atrial fibrillation (AF) is a major contributor to the global cardiovascular
disease burden. The clinical profile and outcomes of AF patients with valvular heart
diseases in sub-Saharan Africa (SSA) have not ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.
(Biol Psychiatry, 2015-02-15)
BACKGROUND: Anxiety produced by environmental threats can impair goal-directed processing
and is associated with a range of psychiatric disorders, particularly when aversive
events occur unpredictably. The prefrontal cortex ...
Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients.
(Ann Am Thorac Soc, 2016-03)
RATIONALE: Limitations in methods for the rapid diagnosis of hospital-acquired infections
often delay initiation of effective antimicrobial therapy. New diagnostic approaches
offer potential clinical and cost-related improvements ...
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.
(Transl Psychiatry, 2015-12-15)
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event,
differing on a variety of sensory and affective ...
Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection.
(PLoS One, 2015)
BACKGROUND: Nonsynonymous single nucleotide polymorphisms (SNPs) in fibronectin binding
protein A (fnbA) of Staphylococcus aureus are associated with cardiac device infections.
However, the role of fnbA SNPs in S. aureus ...
Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
(Ann Neurol, 2015-04)
OBJECTIVE: A study was undertaken to determine whether better cognitive functioning
at midlife among more physically fit individuals reflects neuroprotection, by which
fitness protects against age-related cognitive decline, ...
Psychiatric correlates of snuff and chewing tobacco use.
(PLoS One, 2014)
Compared to the association between cigarette smoking and psychiatric disorders, relatively
little is known about the relationship between smokeless tobacco use and psychiatric
disorders. To identify the psychiatric correlates ...
Initiation of antiretroviral therapy in HIV-infected adults with skin complaints in northern Tanzania.
(Int J Dermatol, 2015-01)
Abnormal skin findings are identified in over 90% of human immunodeficiency virus
(HIV)-infected persons globally. A prospective cohort study of HIV-infected patients
with skin complaints commencing antiretroviral therapy ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...