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A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.
(PloS one, 2014-01)
Psychosocial stress is well known to be positively associated with subsequent depressive
symptoms. Cortisol response to stress may be one of a number of biological mechanisms
that links psychological stress to depressive ...
PhenX RISING: real world implementation and sharing of PhenX measures.
(BMC Med Genomics, 2014-03-20)
BACKGROUND: The purpose of this manuscript is to describe the PhenX RISING network
and the site experiences in the implementation of PhenX measures into ongoing population-based
genomic studies. METHODS: Eighty PhenX measures ...
The dynamics of proactive and reactive cognitive control processes in the human brain.
(J Cogn Neurosci, 2014-05)
In this study, we leveraged the high temporal resolution of EEG to examine the neural
mechanisms underlying the flexible regulation of cognitive control that unfolds over
different timescales. We measured behavioral and ...
Randomized trial on mindfulness training for smokers targeted to a disadvantaged population.
(Subst Use Misuse, 2014-04)
We report the results of a randomized trial comparing a novel smoking cessation treatment
Mindfulness Training for Smokers (MTS) to a usual care therapy (Controls), which included
the availability of a tobacco quit line ...
The human antibody response to the surface of Mycobacterium tuberculosis.
(PLoS One, 2014)
BACKGROUND: Vaccine-induced human antibodies to surface components of Haemophilus
influenzae and Streptococcus pneumonia are correlated with protection. Monoclonal
antibodies to surface components of Mycobacterium tuberculosis ...
A randomized controlled trial of standard versus intensified tuberculosis diagnostics on treatment decisions by physicians in Northern Tanzania.
(BMC Infect Dis, 2014-02-20)
BACKGROUND: Routine tuberculosis culture remains unavailable in many high-burden areas,
including Tanzania. This study sought to determine the impact of providing mycobacterial
culture results over standard of care ...
Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis.
(J Autoimmun, 2014-08)
Muscle specific tyrosine kinase myasthenia gravis (MuSK MG) is a form of autoimmune
MG that predominantly affects women and has unique clinical features, including prominent
bulbar weakness, muscle atrophy, and excellent ...
A genome-wide association study of variants associated with acquisition of Staphylococcus aureus bacteremia in a healthcare setting.
(BMC Infect Dis, 2014-02-13)
BACKGROUND: Humans vary in their susceptibility to acquiring Staphylococcus aureus
infection, and research suggests that there is a genetic basis for this variability.
Several recent genome-wide association studies (GWAS) ...
Blood pressure level impacts risk of death among HIV seropositive adults in Kenya: a retrospective analysis of electronic health records.
(BMC Infect Dis, 2014-05-22)
BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) infection
is increasingly due to non-communicable causes. This has been observed mostly in developed
countries and the routine care of HIV infected ...
The secret ingredient in mindfulness interventions? A case for practice quality over quantity.
(J Couns Psychol, 2014-07)
As mindfulness-based interventions become increasingly widespread, interest has grown
in better understanding which features of these treatments produce beneficial effects.
The present study examined the relative contribution ...