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Establishment and maintenance of a PBMC repository for functional cellular studies in support of clinical vaccine trials.
(J Immunol Methods, 2014-07)
A large repository of cryopreserved peripheral blood mononuclear cells (PBMCs) samples
was created to provide laboratories testing the specimens from human immunodeficiency
virus-1 (HIV-1) vaccine clinical trials the material ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Psychiatric correlates of snuff and chewing tobacco use.
(PLoS One, 2014)
Compared to the association between cigarette smoking and psychiatric disorders, relatively
little is known about the relationship between smokeless tobacco use and psychiatric
disorders. To identify the psychiatric correlates ...
Patterns of care quality and prognosis among hospitalized ischemic stroke patients with chronic kidney disease.
(J Am Heart Assoc, 2014-06-05)
BACKGROUND: Relatively little is known about the quality of care and outcomes for
hospitalized ischemic stroke patients with chronic kidney disease (CKD). We examined
quality of care and in-hospital prognoses among patients ...
A randomized Phase 2 trial of telavancin versus standard therapy in patients with uncomplicated Staphylococcus aureus bacteremia: the ASSURE study.
(BMC Infect Dis, 2014-05-23)
BACKGROUND: Staphylococcus aureus bacteremia is a common infection associated with
significant morbidity and mortality. Telavancin is a bactericidal lipoglycopeptide
active against Gram-positive pathogens, including ...
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
(Am J Respir Crit Care Med, 2014-08-15)
RATIONALE: Asthma is prospectively associated with age-related chronic diseases and
mortality, suggesting the hypothesis that asthma may relate to a general, multisystem
phenotype of accelerated aging. OBJECTIVES: To test ...
Acute administration of unacylated ghrelin has no effect on Basal or stimulated insulin secretion in healthy humans.
(Diabetes, 2014-07)
Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite
its inability to activate the classical ghrelin receptor, preclinical studies suggest
that UAG may promote β-cell function. We hypothesized ...
The role of whole brain radiation therapy in the management of melanoma brain metastases.
(Radiat Oncol, 2014-06-22)
BACKGROUND: Brain metastases are common in patients with melanoma, and optimal management
is not well defined. As melanoma has traditionally been thought of as "radioresistant,"
the role of whole brain radiation therapy ...
The secret ingredient in mindfulness interventions? A case for practice quality over quantity.
(J Couns Psychol, 2014-07)
As mindfulness-based interventions become increasingly widespread, interest has grown
in better understanding which features of these treatments produce beneficial effects.
The present study examined the relative contribution ...
Randomized trial comparing mindfulness training for smokers to a matched control.
(J Subst Abuse Treat, 2014-09)
Smoking continues to take an enormous toll on society, and although most smokers would
like to quit, most are unsuccessful using existing therapies. These findings call
on researchers to develop and test therapies that provide ...