Now showing items 1-10 of 1712
Plasticity in the lung: making and breaking cell identity
On the Null Distribution of Bayes Factors in Linear Regression
(Journal of the American Statistical Association, 2017-07-27)
© 2018 The Author(s). Published with license by Taylor & Francis We show that under the null, the (Formula presented.) is asymptotically distributed as a weighted sum of chi-squared random variables with a shifted mean. ...
Toll-like receptor activation as a biomarker in traumatically injured patients
(Journal of Surgical Research, 2018-11-01)
© 2018 Elsevier Inc. Background: Surgical insult and trauma have been shown to cause dysregulation of the immune and inflammatory responses. Interaction of damage-associated molecular patterns (DAMPs) with toll-like receptors ...
Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.
(Cell host & microbe, 2018-06)
HIV-1 broadly neutralizing antibodies (bnAbs) require high levels of activation-induced cytidine deaminase (AID)-catalyzed somatic mutations for optimal neutralization potency. Probable mutations occur at sites of frequent ...
The CapZ interacting protein Rcsd1 is required for cardiogenesis downstream of Wnt11a in Xenopus laevis
(Developmental Biology, 2017-04)
Strong Selection at MHC in Mexicans since Admixture.
(PLoS genetics, 2016-02-10)
Mexicans are a recent admixture of Amerindians, Europeans, and Africans. We performed local ancestry analysis of Mexican samples from two genome-wide association studies obtained from dbGaP, and discovered that at the MHC ...
Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion.
In the absence of salient sensory cues to guide behavior, animals must still execute sequences of motor actions in order to forage and explore. How such successive motor actions are coordinated to form global locomotion ...
An updated overview on Wnt signaling pathways: a prelude for more
(Circulation Research, 2010-06-25)
A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study.
(Translational vision science & technology, 2017-03-21)
We use semiautomated segmentation of fluorescein angiography (FA) to determine whether anti-vascular endothelial growth factor (VEGF) treatment for diabetic macular edema (DME) differentially affects microaneurysm (MA)-associated ...
Neuronal correlates of serial decision-making in the supplementary eye field
Human behavior is influenced by serial decision-making: past decisions affect choices that set the context for selecting future options. A primate brain region that may be involved in linking decisions across time is the ...