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Genetic variant of PRKAA1 and gastric cancer risk in an eastern Chinese population. 

Qiu, Li-Xin; He, Jing; Cheng, Lei; Zhou, Fei; Wang, Meng-Yun; Sun, Meng-Hong; Zhou, Xiao-Yan; ... (15 authors) (Oncotarget, 2015-12)
Published data on the association between PRKAA1 rs13361707 T > C polymorphism and gastric cancer (GCa) susceptibility were inconclusive. To derive a more precise estimation of the association, we conducted a large-scale ...
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Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations. 

Zhu, Mei-Ling; Shi, Ting-Yan; Hu, Hai-Chuan; He, Jing; Wang, Mengyun; Jin, Li; Yang, Ya-Jun; ... (15 authors) (PloS one, 2012-01)
BACKGROUND: Excision repair cross complementing group 5 (ERCC5 or XPG) plays an important role in regulating DNA excision repair; its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity and thus ...
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Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population. 

Zhou, Fei; Cheng, Lei; Qiu, Li-Xin; Wang, Meng-Yun; Li, Jin; Sun, Meng-Hong; Yang, Ya-Jun; ... (11 authors) (Oncotarget, 2016-05)
The interleukin-6 (IL-6)/JAK/STAT3 signaling pathway plays a central role in inflammation-mediated cancers, including gastric cancer (GCa). We evaluated associations between 10 potentially functional single nucleotide ...
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Polymorphisms in the AKT1 and AKT2 genes and oesophageal squamous cell carcinoma risk in an Eastern Chinese population. 

Zhu, Jinhong; Wang, Mengyun; He, Jing; Zhu, Meiling; Wang, Jiu-Cun; Jin, Li; Wang, Xiao-Feng; ... (10 authors) (Journal of cellular and molecular medicine, 2016-04)
Ethnic Han Chinese are at high risk of developing oesophageal squamous cell carcinoma (ESCC). Aberrant activation of the AKT signalling pathway is involved in many cancers, including ESCC. Some single nucleotide polymorphisms ...
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PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population. 

Qiu, Li-Xin; Cheng, Lei; He, Jing; Zhou, Zhi-Rui; Wang, Meng-Yun; Zhou, Fei; Guo, Wei-Jian; ... (16 authors) (Oncotarget, 2016-02)
The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. The associations between the PSCA rs2294008 and rs2976392 ...
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A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population. 

Wang, Meng-Yun; He, Jing; Zhu, Mei-Ling; Teng, Xiao-Yan; Li, Qiao-Xin; Sun, Meng-Hong; Wang, Xiao-Feng; ... (12 authors) (Scientific reports, 2016-01-28)
AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric ...
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Genetic variant rs4072037 of MUC1 and gastric cancer risk in an Eastern Chinese population. 

Qiu, Li-Xin; Hua, Rui-Xi; Cheng, Lei; He, Jing; Wang, Meng-Yun; Zhou, Fei; Zhu, Xiao-Dong; ... (16 authors) (Oncotarget, 2016-03)
Published data on the association between the MUC1 rs4072037A > G polymorphism and gastric cancer (GCa) risk were inconclusive. To derive a more precise estimation of the association, we conducted a large GCa study of 1,124 ...
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Associations of genotypes and haplotypes of IL-17 with risk of gastric cancer in an eastern Chinese population. 

Zhou, Fei; Qiu, Li-Xin; Cheng, Lei; Wang, Meng-Yun; Li, Jin; Sun, Meng-Hong; Yang, Ya-Jun; ... (11 authors) (Oncotarget, 2016-12)
Interleukin-17 plays a crucial role in inflammation-related carcinogenesis. We hypothesize that genetic variants in IL-17 are associated with gastric cancer (GCa) risk, and we genotyped five potentially functional single ...

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AuthorJin, Li (8)
Wang, Jiu-Cun (8)
Yang, Ya-Jun (8)Sun, Meng-Hong (7)Wei, Qing-Yi (7)He, Jing (6)Wang, Meng-Yun (6)Wang, Ya-Nong (6)Cheng, Lei (5)Li, Jin (5)... View MoreDate Issued2016 (6)2012 (1)2015 (1)Type
Journal article (8)
SubjectFemale (8)Humans (8)Male (8)
Middle Aged (8)
Polymorphism, Single Nucleotide (8)
Risk Factors (8)
Asian Continental Ancestry Group (7)Aged (6)Case-Control Studies (6)Genetic Predisposition to Disease (6)... View MoreAffiliation of Duke Author(s)Basic Science Departments (8)Clinical Science Departments (8)Duke (8)Duke Cancer Institute (8)Institutes and Centers (8)
Medicine (8)
Medicine, Medical Oncology (8)Population Health Sciences (8)School of Medicine (8)
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