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Now showing items 1-9 of 9
Comparative effectiveness studies to improve clinical outcomes in end stage renal disease: the DEcIDE patient outcomes in end stage renal disease study.
(BMC Nephrol, 2012-12-06)
BACKGROUND: Evidence is lacking to inform providers' and patients' decisions about
many common treatment strategies for patients with end stage renal disease (ESRD).
METHODS/DESIGN: The DEcIDE Patient Outcomes in ESRD Study ...
Polymorphisms in the ERCC5 gene and risk of esophageal squamous cell carcinoma (ESCC) in Eastern Chinese populations.
(PloS one, 2012-01)
BACKGROUND: Excision repair cross complementing group 5 (ERCC5 or XPG) plays an important
role in regulating DNA excision repair; its functional single nucleotide polymorphisms
(SNPs) may alter DNA repair capacity and thus ...
On the interplay of telomeres, nevi and the risk of melanoma.
(PloS one, 2012-01)
The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres
have been found to be associated with many cancers and with number of nevi, a known
risk factor for melanoma. However, shorter telomeres ...
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
(Subst Abuse Treat Prev Policy, 2012-03-20)
BACKGROUND: Although methadone has been used for the maintenance treatment of opioid
dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug
interactions (MDIs) have been shown to cause ...
Predictors of latent tuberculosis treatment initiation and completion at a U.S. public health clinic: a prospective cohort study.
(BMC Public Health, 2012-06-21)
BACKGROUND: Treatment of latent tuberculosis infection (LTBI) is a key component in
U.S. tuberculosis control, assisted by recent improvements in LTBI diagnostics and
therapeutic regimens. Effectiveness of LTBI therapy, ...
Off-label closure during CLOSURE study.
(J Invasive Cardiol, 2012-11)
BACKGROUND: The role of percutaneous closure of patent foramen ovale (PFO) in patients
with cryptogenic stroke or transient ischemic attack remains controversial. Registry
data have suggested considerable benefit of closure ...
Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.
(PloS one, 2012-01)
Recently, several genome-wide association studies (GWAS) have identified many susceptible
single nucleotide polymorphisms (SNPs) for chronic obstructive pulmonary disease (COPD)
and lung cancer which are two closely related ...
Brucellosis among hospitalized febrile patients in northern Tanzania.
(Am J Trop Med Hyg, 2012-12)
Acute and convalescent serum samples were collected from febrile inpatients identified
at two hospitals in Moshi, Tanzania. Confirmed brucellosis was defined as a positive
blood culture or a ≥ 4-fold increase in ...
Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.
(BMC Health Serv Res, 2012-01-18)
BACKGROUND: Type 2 diabetes is a prevalent chronic condition globally that results
in extensive morbidity, decreased quality of life, and increased health services utilization.
Lifestyle changes can prevent the development ...