Browsing Scholarly Articles by Issue Date
Now showing items 21-40 of 12693
-
Blood RNA alternative splicing events as diagnostic biomarkers for infectious disease
(Cell Reports Methods, 2023-01-01)Assays detecting blood transcriptome changes are studied for infectious disease diagnosis. Blood-based RNA alternative splicing (AS) events, which have not been well characterized in pathogen infection, have potential ... -
Internal Medicine Resident Barriers to Advance Care Planning in the Primary Care Continuity Clinic
(American Journal of Hospice and Palliative Medicine, 2023-01-01)Background: While primary care providers regularly engage in Advance Care Planning (ACP) conversations, it is not well known what challenges resident physicians face to achieving this core competency. Objectives: We aimed ... -
Implementation Science Toolkit for Clinicians: Improving Adoption of Evidence in Practice.
(Dimensions of critical care nursing : DCCN, 2023-01)<h4>Background</h4>Clinicians are often familiar with quality improvement (QI) and evidence-based practice (EBP) processes, which provides guidance into what evidence should be implemented; however, these processes do not ... -
Development of a real-world database for asthma and COPD: The SingHealth-Duke-NUS-GSK COPD and Asthma Real-World Evidence (SDG-CARE) collaboration.
(BMC medical informatics and decision making, 2023-01)<h4>Purpose</h4>The SingHealth-Duke-GlaxoSmithKline COPD and Asthma Real-world Evidence (SDG-CARE) collaboration was formed to accelerate the use of Singaporean real-world evidence in research and clinical care. A centerpiece ... -
Bone morphogenetic protein 10: a novel risk marker of ischaemic stroke in patients with atrial fibrillation.
(European heart journal, 2023-01)<h4>Aims</h4>Biomarkers specifically related to atrial tissue may increase the understanding of the pathophysiology of atrial fibrillation (AF) and further improve risk prediction in this setting. Bone morphogenetic protein ... -
Concordance Between Genomic Alterations Detected by Tumor and Germline Sequencing: Results from a Tertiary Care Academic Center Molecular Tumor Board.
(The oncologist, 2023-01)<h4>Objective</h4>The majority of tumor sequencing currently performed on cancer patients does not include a matched normal control, and in cases where germline testing is performed, it is usually run independently of tumor ... -
PPDPF Promotes the Development of Mutant KRAS-Driven Pancreatic Ductal Adenocarcinoma by Regulating the GEF Activity of SOS1.
(Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023-01)The guanine nucleotide exchange factor (GEF) SOS1 catalyzes the exchange of GDP for GTP on RAS. However, regulation of the GEF activity remains elusive. Here, the authors report that PPDPF functions as an important regulator ... -
A 13-Year-Old Girl With Unilateral Visual Changes.
(Journal of investigative medicine high impact case reports, 2023-01)Neuroretinitis is a condition typically characterized by unilateral optic neuropathy and is most commonly a sequelae of cat scratch disease (CSD) due to infection with Bartonella henselae. Ophthalmologic examination will ... -
SGC-CAMKK2-1: A Chemical Probe for CAMKK2.
(Cells, 2023-01)The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Despite its importance, only a handful of inhibitors of CAMKK2 have ... -
Limited physician knowledge of sarcopenia: A survey.
(Journal of the American Geriatrics Society, 2023-01)<h4>Background</h4>Sarcopenia, a reduction in skeletal muscle mass and function, is a condition that contributes to functional decline and disability in older adults. Although research on this geriatric condition has developed ... -
Anti-HIV Potential of Beesioside I Derivatives as Maturation Inhibitors: Synthesis, 3D-QSAR, Molecular Docking and Molecular Dynamics Simulations.
(International journal of molecular sciences, 2023-01)HIV-1 maturation is the final step in the retroviral lifecycle that is regulated by the proteolytic cleavage of the Gag precursor protein. As a first-in-class HIV-1 maturation inhibitor (MI), bevirimat blocks virion maturation ... -
Deep-tissue SWIR imaging using rationally designed small red-shifted near-infrared fluorescent protein.
(Nature methods, 2023-01)Applying rational design, we developed 17 kDa cyanobacteriochrome-based near-infrared (NIR-I) fluorescent protein, miRFP718nano. miRFP718nano efficiently binds endogenous biliverdin chromophore and brightly fluoresces in ... -
Distressed Work: Chronic Imperatives and Distress in Covid-19 Critical Care.
(The Hastings Center report, 2023-01)This ethnographic study introduces the term "distressed work" to describe the emergence of chronic frictions between moral imperatives for health care workers to keep working and the dramatic increase in distress during ... -
The Trouble with Sustainability
(Sustainability, 2023) -
Prison of the Womb: Gender, Incarceration, and Capitalism on the Gold Coast of West Africa, c. 1500–1957
(Comparative Studies in Society and History, 2023)<jats:title>Abstract</jats:title> <jats:p>To date, studies of imprisonment and incarceration have focused on the growth of male-gendered penal institutions. This essay offers a provocative addition to the global study ... -
What Can Outliers Teach Us About Entrepreneurial Success?
(Journal of Small Business and Enterprise Development, 2023) -
TÁTICAS DO INVISÍVEL EM BRANCO SAI, PRETO FICA (2015): CINEMA, ARQUIVO E MEMÓRIA ÀS MARGENS DE BRASÍLIA
(Revista Iberoamericana, 2022-12-31) -
The pandemic is not the great equalizer: front-line labor and rationing in COVID-19 critical care
(Public Health Action, 2022-12-21)<jats:p><jats:bold>BACKGROUND:</jats:bold> Framed as “the great-equalizer,” the COVID-19 pandemic has intensified pressure to adapt critical care labor and resulted in rationing by healthcare workers across the ... -
Water quality implications of the neutralization of acid mine drainage with coal fly ash from India and the United States
(Fuel, 2022-12-15)Subsurface coal mining often induces the formation of acid mine drainage (AMD) in active and abandoned coal mines while coal combustion generates coal combustion residuals (CCR), including fly ash (FA), with elevated levels ... -
EAP Courses in Joint-Venture Institutions: A Needs Analysis Based on Learner Perceptions
(Indonesian Journal of English Language Teaching and Applied Linguistics, 2022-12-12)With the increase in English medium instruction (EMI) in non-English-speaking countries, the role of EAP in preparing learners for the academic tasks that they will face is enhanced. Joint-venture universities (JVUs), ...
