Browsing Scholarly Articles by Issue Date

Characterization of In-Flight Medical Events Involving Children on Commercial Airline Flights

Rotta, Alexandre; Alves, Paulo M; Nerwich, Neil; Shein, Steven L (Annals of Emergency Medicine, 2019-07)

The RNA-binding protein DND1 acts Sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming.

Keene, Jack; Capel, Blanche; Ruthig, Victor A; Friedersdorf, Matthew B; Garness, Jason A; Munger, Steve C; Bunce, Corey (Development (Cambridge, England), 2019-06-28)

The adult spermatogonial stem cell population arises from pluripotent primordial germ cells (PGCs) that enter the fetal testis around embryonic day (E)10.5. PGCs undergo rapid mitotic proliferation, then enter prolonged ...

Photoreceptors in a Mouse Model of Leigh Syndrome are Capable of Normal Light-Evoked Signaling.

Gospe, Sidney; Arshavsky, Vadim; Travis, Amanda M; Kolesnikov, Alexander V; Klingeborn, Mikael; Wang, Luyu; Kefalov, Vladimir J (The Journal of biological chemistry, 2019-06-27)

Mitochondrial dysfunction is an important cause of heritable vision loss. Mutations affecting mitochondrial bioenergetics may lead to isolated vision loss or life-threatening systemic disease, depending on a mutation's severity. ...

Predicting the Risk of Huntington's Disease with Multiple Longitudinal Biomarkers.

Luo, Sheng; Li, Fan; Li, Kan; Li, Cai (Journal of Huntington's disease, 2019-06-22)

BACKGROUND:Huntington's disease (HD) has gradually become a public health threat, and there is a growing interest in developing prognostic models to predict the time for HD diagnosis. OBJECTIVE:This study aims to develop ...

Surgical correction of severe adult lumbar scoliosis (major curves ≥ 75°): retrospective analysis with minimum 2-year follow-up.

Shaffrey, Christopher; Buell, Thomas J; Chen, Ching-Jen; Nguyen, James H; Christiansen, Peter A; Murthy, Saikiran G; Buchholz, Avery L; ... (10 authors) (Journal of neurosurgery. Spine, 2019-06-21)

OBJECTIVE:Prior reports have demonstrated the efficacy of surgical correction for adult lumbar scoliosis. Many of these reports focused on mild to moderate scoliosis. The authors' objective was to report their experience ...

Mistakes, I've Had a Few.

Brown, Trig (Journal of general internal medicine, 2019-06-19)

Meniscus-Derived Matrix Scaffolds Promote the Integrative Repair of Meniscal Defects.

Weinberg, Joe; McNulty, Amy; Ruprecht, Jacob C; Waanders, Taylor D; Rowland, Christopher R; Nishimuta, James F; Glass, Katherine A; ... (10 authors) (Scientific reports, 2019-06-18)

Meniscal tears have a poor healing capacity, and damage to the meniscus is associated with significant pain, disability, and progressive degenerative changes in the knee joint that lead to osteoarthritis. Therefore, strategies ...

The Lipid A 1-Phosphatase, LpxE, Functionally Connects Multiple Layers of Bacterial Envelope Biogenesis.

Zhou, Pei; Guan, Ziqiang; Zhao, Jinshi; An, Jinsu; Hwang, Dohyeon; Wu, Qinglin; Wang, Su; ... (10 authors) (mBio, 2019-06-18)

Although distinct lipid phosphatases are thought to be required for processing lipid A (component of the outer leaflet of the outer membrane), glycerophospholipid (component of the inner membrane and the inner leaflet of ...

Outcomes of Lymph Node Dissection for Non-metastatic Pancreatic Neuroendocrine Tumors: A Propensity Score-Weighted Analysis of the National Cancer Database.

Luo, Sheng; Blazer, Dan; Mao, Rui; Zhao, Hong; Li, Kan; Turner, Megan; Cai, Jian-Qiang (Annals of surgical oncology, 2019-06-17)

BACKGROUND:Although the National Comprehensive Cancer Network (NCCN) guidelines recommend use of lymph node dissection (LND) in patients with pancreatic neuroendocrine tumors (pNETs) > 2 cm, there is limited evidence to ...

Law Enforcement and Clinician Partnerships: Training of Trainers for CIT Teams in Liberia, West Africa.

Kohrt, Brandon; Boazak, Mina; Gwaikolo, Wilfred; Yoss, Sarah; Sonkarlay, Sehwah; Strode, Pat; Compton, Michael T; ... (8 authors) (Psychiatric services (Washington, D.C.), 2019-06-12)

The crisis intervention team (CIT) model was developed in the United States to align law enforcement goals with those of mental health advocates and service users. Liberia is the first low-income country where CIT has been ...

Sweet neurons inhibit texture discrimination by signaling TMC-expressing mechanosensitive neurons in Drosophila.

Yang, Rebecca; Wu, Shun-Fan; Ja, Ya-Long; Zhang, Yi-Jie (eLife, 2019-06-11)

Integration of stimuli of different modalities is an important but incompletely understood process during decision making. Here, we show that Drosophila are capable of integrating mechanosensory and chemosensory information ...

Expanding the Concept of Diagnostic Reference Levels to Noise and Dose Reference Levels in CT.

Ria, Francesco; Davis, Joseph T; Solomon, Justin B; Wilson, Joshua M; Smith, Taylor B; Frush, Donald P; Samei, Ehsan (AJR. American journal of roentgenology, 2019-06-10)

OBJECTIVE. Diagnostic reference levels were developed as guidance for radiation dose in medical imaging and, by inference, diagnostic quality. The objective of this work was to expand the concept of diagnostic reference ...

Egg Consumption and Risk of Total and Cause-Specific Mortality: An Individual-Based Cohort Study and Pooling Prospective Studies on Behalf of the Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group.

Pencina, Michael; Mazidi, Mohsen; Katsiki, Niki; Mikhailidis, Dimitri P; Banach, Maciej (Journal of the American College of Nutrition, 2019-06-07)

The associations of egg consumption with total, coronary heart disease (CHD), and stroke mortality are poorly understood. We prospectively evaluated the link between total, CHD, and stroke mortality with egg consumption ...