Browsing Scholarly Articles by Submit Date
Now showing items 21-40 of 8397
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Correction: In Vitro Pre-Clinical Validation of Suicide Gene Modified Anti-CD33 Redirected Chimeric Antigen Receptor T-Cells for Acute Myeloid Leukemia.
(PloS one, 2017-01)[This corrects the article DOI: 10.1371/journal.pone.0166891.]. -
Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study.
(The Lancet. Oncology, 2017-08)BACKGROUND:Internal tandem duplication mutations in FLT3 are common in acute myeloid leukaemia and are associated with rapid relapse and short overall survival. The clinical benefit of FLT3 inhibitors in patients with acute ... -
A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia.
(PloS one, 2014-01)An open-label phase I/II study of single-agent obatoclax determined a maximum tolerated dose (MTD) and schedule, safety, and efficacy in older patients (≥ 70 yr) with untreated acute myeloid leukemia (AML).Phase I evaluated ... -
Phase 1/2 trial of GCLAM with dose-escalated mitoxantrone for newly diagnosed AML or other high-grade myeloid neoplasms.
(Leukemia, 2018-11)Outcomes with "7 + 3" are often unsatisfactory in acute myeloid leukemia (AML). Trials demonstrating improved outcomes with high-dose cytarabine, addition of cladribine, or escalated anthracycline doses prompted a phase ... -
Relative survival following response to 7 + 3 versus azacytidine is similar in acute myeloid leukemia and high-risk myelodysplastic syndromes: an analysis of four SWOG studies.
(Leukemia, 2019-02)Here we quantify and compare the absolute and relative overall survival (OS) benefits conveyed by complete remission (CR) in AML and high-risk MDS, and by CR with incomplete count recovery (CRi) in AML and by hematologic ... -
Genomic Biomarkers to Predict Resistance to Hypomethylating Agents in Patients With Myelodysplastic Syndromes Using Artificial Intelligence.
(JCO precision oncology, 2019-01)PURPOSE:We developed an unbiased framework to study the association of several mutations in predicting resistance to hypomethylating agents (HMAs) in patients with myelodysplastic syndromes (MDS), analogous to consumer and ... -
Dietary Variability in Redtail Monkeys (Cercopithecus ascanius schmidti) of Kibale National Park, Uganda: the Role of Time, Space, and Hybridization
(International Journal of Primatology, 2017-10-01)© 2017, Springer Science+Business Media, LLC. Studies of the diet of different groups of the same species allow us to understand intraspecific dietary variability. I collected dietary data from six neighboring groups of ... -
Diet of red-legged sun squirrels (Heliosciurus rufobrachium Waterhouse) in Kibale National Park, Uganda: Implications for seed defence
(African Journal of Ecology, 2019-01-01) -
Emergent productivity regimes of river networks
(Limnology and Oceanography Letters, 2019-10) -
Regression of Epileptogenesis by Inhibiting Tropomyosin Kinase B Signaling following a Seizure.
(Annals of neurology, 2019-12)OBJECTIVE:Temporal lobe epilepsy (TLE) is a devastating disease in which seizures persist in 35% of patients despite optimal use of antiseizure drugs. Clinical and preclinical evidence implicates seizures themselves as one ... -
Germline Genetic Testing: What the Breast Surgeon Needs to Know.
(Annals of surgical oncology, 2019-07)PURPOSE:The American Society of Breast Surgeons (ASBrS) sought to provide educational guidelines for breast surgeons on how to incorporate genetic information and genomics into their practice. METHODS:A comprehensive ... -
The Influence of Age on the Histopathology and Prognosis of Atypical Breast Lesions.
(The Journal of surgical research, 2019-09)BACKGROUND:Although several prognostic variables and risk factors for breast cancer are age-related, the association between age and risk of cancer with breast atypia is controversial. This study aimed to compare the type ... -
The impact of chemotherapy sequence on survival in node-positive invasive lobular carcinoma.
(Journal of surgical oncology, 2019-08)BACKGROUND AND OBJECTIVES:We sought to evaluate the impact of chemotherapy sequence on survival by comparing node-positive invasive lobular carcinoma (ILC) patients who received neoadjuvant (NACT) and adjuvant (ACT) chemotherapy. ... -
Clinical and pathological stage discordance among 433,514 breast cancer patients.
(American journal of surgery, 2019-10)BACKGROUND:We aim to determine clinical and pathological stage discordance rates and to evaluate factors associated with discordance. METHODS:Adults with clinical stages I-III breast cancer were identified from the National ... -
Nodal Response to Neoadjuvant Chemotherapy Predicts Receipt of Radiation Therapy after Breast Cancer Diagnosis.
(International journal of radiation oncology, biology, physics, 2019-10-31)BACKGROUND:Pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) is associated with improved overall survival (OS) in breast-cancer patients, but it is unclear how post-NACT response influences radiotherapy ... -
Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever.
(BMC infectious diseases, 2019-10-28)BACKGROUND:Antibiotic resistance is rising at disturbing rates and contributes to the deaths of millions of people yearly. Antibiotic resistant infections disproportionately affect those with immunocompromising conditions, ... -
Pulmonary Edema and Diastolic Heart Failure in the Perioperative Period.
(Case reports in anesthesiology, 2018-01-23)Heart failure with preserved ejection fraction (HFPEF) is a diagnosis encountered with increasing frequency in the aging population. We present a case of postoperative pulmonary edema in 63-year-old male with HFPEF. This ... -
Arterial Blood Gas Analysis in Breath-Hold Divers at Depth.
(Frontiers in physiology, 2018-01)The present study aimed to evaluate the partial pressure of arterial blood gases in breath-hold divers performing a submersion at 40 m. Eight breath-hold divers were enrolled for the trials held at "Y-40 THE DEEP JOY" pool ... -
Environmental Physiology and Diving Medicine.
(Frontiers in psychology, 2018-01)Man's experience and exploration of the underwater environment has been recorded from ancient times and today encompasses large sections of the population for sport enjoyment, recreational and commercial purpose, as well ...
