Now showing items 1-8 of 8

    • B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity. 

      Yi, John S; Russo, Melissa A; Massey, Janice M; Juel, Vern; Hobson-Webb, Lisa D; Gable, Karissa; Raja, Shruti M; ... (10 authors) (Front Neurol, 2017)
      Myasthenia gravis (MG) is a T cell-dependent, B cell-mediated disease. The mechanisms for loss of self-tolerance in this disease are not well understood, and recently described regulatory B cell (Breg) subsets have not been ...
    • Characterization of B cells in muscle-specific kinase antibody myasthenia gravis. 

      Guptill, Jeffrey T; Yi, John S; Sanders, Donald B; Guidon, Amanda C; Juel, Vern C; Massey, Janice M; Howard, James F; ... (11 authors) (Neurol Neuroimmunol Neuroinflamm, 2015-04)
      OBJECTIVE: To characterize B-cell subsets in patients with muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG). METHODS: In accordance with Human Immunology Project Consortium guidelines, we performed polychromatic ...
    • Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis. 

      Yi, JS; Guidon, A; Sparks, S; Osborne, R; Juel, VC; Massey, JM; Sanders, DB; ... (9 authors) (J Autoimmun, 2014-08)
      Muscle specific tyrosine kinase myasthenia gravis (MuSK MG) is a form of autoimmune MG that predominantly affects women and has unique clinical features, including prominent bulbar weakness, muscle atrophy, and excellent ...
    • Establishment of normative ranges of the healthy human immune system with comprehensive polychromatic flow cytometry profiling. 

      Yi, John S; Rosa-Bray, Marilyn; Staats, Janet; Zakroysky, Pearl; Chan, Cliburn; Russo, Melissa A; Dumbauld, Chelsae; ... (11 authors) (PloS one, 2019-01)
      Existing normative flow cytometry data have several limitations including small sample sizes, incompletely described study populations, variable flow cytometry methodology, and limited depth for defining lymphocyte ...
    • Myasthenia gravis. 

      Juel, Vern C; Massey, Janice M (Orphanet J Rare Dis, 2007-11-06)
      Myasthenia gravis (MG) is a rare, autoimmune neuromuscular junction disorder. Contemporary prevalence rates approach 1/5,000. MG presents with painless, fluctuating, fatigable weakness involving specific muscle groups. Ocular ...
    • Normative dataset for plasma cytokines in healthy human adults. 

      Li, Yingkai; Yi, John S; Russo, Melissa A; Rosa-Bray, Marilyn; Weinhold, Kent J; Guptill, Jeffrey T (Data in brief, 2021-04)
      We determined normative data for plasma cytokines established from a cohort of 126 carefully screened healthy adults aged 18 to 64 years. Participants were enrolled to ensure an even age and sex distribution and to include ...
    • Prolonged B-cell depletion in MuSK myasthenia gravis following rituximab treatment. 

      Yi, John S; Decroos, Emily C; Sanders, Donald B; Weinhold, Kent J; Guptill, Jeffrey T (Muscle Nerve, 2013-12)
    • Small-fiber neuropathy in pompe disease: first reported cases and prospective screening of a clinic cohort. 

      Hobson-Webb, Lisa D; Austin, Stephanie L; Jain, Sneha; Case, Laura E; Greene, Karla; Kishnani, Priya S (Am J Case Rep, 2015-04-03)
      BACKGROUND: Prior autopsy reports demonstrate glycogen deposition in Schwann cells of the peripheral nerves in patients with infantile and late-onset Pompe disease (LOPD), but little is known about associated clinical features. ...