Now showing items 1-6 of 6

    • B10 Cell Frequencies and Suppressive Capacity in Myasthenia Gravis Are Associated with Disease Severity. 

      Balderson, Kristina; Gable, Karissa Lorraine; Guptill, JT; Hobson-Webb, Lisa Deneen; Juel, Vern Charles; Massey, JM; Raja, SM; ... (10 authors) (Front Neurol, 2017)
      Myasthenia gravis (MG) is a T cell-dependent, B cell-mediated disease. The mechanisms for loss of self-tolerance in this disease are not well understood, and recently described regulatory B cell (Breg) subsets have not been ...
    • Characterization of B cells in muscle-specific kinase antibody myasthenia gravis. 

      Bartoccioni, E; Evoli, A; Guidon, Amanda C; Guptill, JT; Howard, JF; Juel, Vern Charles; Massey, JM; ... (11 authors) (Neurol Neuroimmunol Neuroinflamm, 2015-04)
      OBJECTIVE: To characterize B-cell subsets in patients with muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG). METHODS: In accordance with Human Immunology Project Consortium guidelines, we performed polychromatic ...
    • Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis. 

      Guidon, Arnaud; Guptill, JT; Juel, Vern Charles; Massey, JM; Osborne, R; Sanders, DB; Sparks, S; ... (9 authors) (J Autoimmun, 2014-08)
      Muscle specific tyrosine kinase myasthenia gravis (MuSK MG) is a form of autoimmune MG that predominantly affects women and has unique clinical features, including prominent bulbar weakness, muscle atrophy, and excellent ...
    • Myasthenia gravis. 

      Juel, Vern Charles; Massey, JM (Orphanet J Rare Dis, 2007-11-06)
      Myasthenia gravis (MG) is a rare, autoimmune neuromuscular junction disorder. Contemporary prevalence rates approach 1/5,000. MG presents with painless, fluctuating, fatigable weakness involving specific muscle groups. Ocular ...
    • Prolonged B-cell depletion in MuSK myasthenia gravis following rituximab treatment. 

      Decroos, EC; Guptill, JT; Sanders, DB; Weinhold, Kent James; Yi, John S (Muscle Nerve, 2013-12)
    • Small-fiber neuropathy in pompe disease: first reported cases and prospective screening of a clinic cohort. 

      Hobson-Webb, Lisa Deneen; Austin, Stephanie; Jain, S; Case, Laura Elizabeth; Greene, Karla; Kishnani, Priya Sunil (Am J Case Rep, 2015-04-03)
      BACKGROUND: Prior autopsy reports demonstrate glycogen deposition in Schwann cells of the peripheral nerves in patients with infantile and late-onset Pompe disease (LOPD), but little is known about associated clinical features. ...