Now showing items 1-2 of 2

    • Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species. 

      Alexandrov, A; Baranay, P; Bechner, M; Birol, I; Boisvert, S; Bradnam, KR; Chapman, JA; ... (91 authors) (Gigascience, 2013-07-22)
      BACKGROUND: The process of generating raw genome sequence data continues to become cheaper, faster, and more accurate. However, assembly of such data into high-quality, finished genome sequences remains challenging. Many ...
    • Hybrid error correction and de novo assembly of single-molecule sequencing reads. 

      Ganapathy, G; Howard, JT; Jarvis, Erich David; Koren, Sergey; Martin, J; McCombie, WR; Phillippy, Adam M; ... (11 authors) (Nat Biotechnol, 2012-07-01)
      Single-molecule sequencing instruments can generate multikilobase sequences with the potential to greatly improve genome and transcriptome assembly. However, the error rates of single-molecule reads are high, which has limited ...