Browsing Scholarly Articles by Subject "R-Loop Structures"

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BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation.

Edwards, Drake S; Maganti, Rohin; Tanksley, Jarred P; Luo, Jie; Park, James JH; Balkanska-Sinclair, Elena; Ling, Jinjie; ... (8 authors) (Cell reports, 2020-09)

Effective spatio-temporal control of transcription and replication during S-phase is paramount to maintaining genomic integrity and cell survival. Dysregulation of these systems can lead to conflicts between the transcription ...