Now showing items 1-3 of 3
Whole-Genome Sequencing of a Single Proband Together with Linkage Analysis Identifies a Mendelian Disease Gene
(PLoS Genetics, 2010-06-17)
The characterization of twenty sequenced human genomes.
(PLoS Genet, 2010-09-09)
We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...
Host determinants of HIV-1 control in African Americans.
(J Infect Dis, 2010-04-15)
We performed a whole-genome association study of human immunodeficiency virus type 1 (HIV-1) set point among a cohort of African Americans (n = 515), and an intronic single-nucleotide polymorphism (SNP) in the HLA-B gene ...