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The Color of COVID-19: Structural Racism and the Disproportionate Impact of the Pandemic on Older Black and Latinx Adults. 

Garcia, Marc A; Homan, Patricia A; García, Catherine; Brown, Tyson H (The journals of gerontology. Series B, Psychological sciences and social sciences, 2021-02)
<h4>Objectives</h4>The aim of this evidence-based theoretically informed article was to provide an overview of how and why the COVID-19 outbreak is particularly detrimental for the health of older Black and Latinx ...
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Gaps in Hypertension Guidelines in Low- and Middle-Income Versus High-Income Countries: A Systematic Review. 

Owolabi, Mayowa; Olowoyo, Paul; Miranda, J Jaime; Akinyemi, Rufus; Feng, Wuwei; Yaria, Joseph; Makanjuola, Tomiwa; ... (30 authors) (Hypertension (Dallas, Tex. : 1979), 2016-12)
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A phase I study of ABT-510 plus bevacizumab in advanced solid tumors. 

Uronis, Hope E; Cushman, Stephanie M; Bendell, Johanna C; Blobe, Gerard C; Morse, Michael A; Nixon, Andrew B; Dellinger, Andrew; ... (13 authors) (Cancer Med, 2013-06)
Targeting multiple regulators of tumor angiogenesis have the potential to improve treatment efficacy. Bevacizumab is a monoclonal antibody directed against vascular endothelial growth factor and ABT-510 is a synthetic analog ...
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Using a Regent Aortic Valve in a Small Annulus Mitral Position Is a Viable Option. 

Barac, Yaron D; Zwischenberger, Brittany; Schroder, Jacob N; Daneshmand, Mani A; Haney, John C; Gaca, Jeffrey G; Wang, Andrew; ... (9 authors) (The Annals of thoracic surgery, 2018-04)
BACKGROUND:Outcome of mitral valve replacement in extreme scenarios of small mitral annulus with the use of the Regent mechanical aortic valve is not well documented. METHODS:Records were examined in 31 consecutive patients ...
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Trends in functional disability and cognitive impairment among the older adult in China up to 2060: estimates from a dynamic multi-state population model. 

Ansah, John P; Chiu, Chi-Tsun; Wei-Yan, Aloysius Chia; Min, Tessa Lui Shi; Matchar, David B (BMC geriatrics, 2021-06-22)
<h4>Background</h4>Available evidence suggests that cognitive impairment (CI), which leads to deficits in episodic memory, executive functions, visual attention, and language, is associated with difficulties in the capacity ...
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Genome-wide gene-environment interaction analysis for asbestos exposure in lung cancer susceptibility. 

Wei, Sheng; Wang, Li-E; McHugh, Michelle K; Han, Younghun; Xiong, Momiao; Amos, Christopher I; Spitz, Margaret R; ... (8 authors) (Carcinogenesis, 2012-08)
Asbestos exposure is a known risk factor for lung cancer. Although recent genome-wide association studies (GWASs) have identified some novel loci for lung cancer risk, few addressed genome-wide gene-environment interactions. ...
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Two-stage genome-wide association study identifies a novel susceptibility locus associated with melanoma. 

Ransohoff, Katherine J; Wu, Wenting; Cho, Hyunje G; Chahal, Harvind C; Lin, Yuan; Dai, Hong-Ji; Amos, Christopher I; ... (13 authors) (Oncotarget, 2017-03)
Genome-wide association studies have identified 21 susceptibility loci associated with melanoma. These loci implicate genes affecting pigmentation, nevus count, telomere maintenance, and DNA repair in melanoma risk. Here, ...
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Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality. 

Kravchenko, J; Akushevich, I; Abernathy, AP; Holman, S; Ross, WG; Lyerly, HK (Int J Chron Obstruct Pulmon Dis, 2014)
BACKGROUND: The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina ...
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Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial. 

Investigators, NINDSNET-PDFS-ZONE (Lancet Neurol, 2015-08)
BACKGROUND: A systematic assessment of potential disease-modifying compounds for Parkinson's disease concluded that pioglitazone could hold promise for the treatment of patients with this disease. We assessed the effect ...
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Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations. 

Attur, M; Wang, HY; Kraus, VB; Bukowski, JF; Aziz, N; Krasnokutsky, S; Samuels, J; ... (11 authors) (Ann Rheum Dis, 2010-05)
BACKGROUND: A lack of biomarkers that identify patients at risk for severe osteoarthritis (OA) complicates development of disease-modifying OA drugs. OBJECTIVE: To determine whether inflammatory genetic markers could stratify ...
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