Search
Now showing items 1-10 of 1172
Biogeography in deep time - What do phylogenetics, geology, and paleoclimate tell us about early platyrrhine evolution?
(Mol Phylogenet Evol, 2015-01)
Molecular data have converged on a consensus about the genus-level phylogeny of extant
platyrrhine monkeys, but for most extinct taxa and certainly for those older than
the Pleistocene we must rely upon morphological evidence ...
Anthropology. New World monkey origins.
(Science, 2015-03-06)
Rapid, accurate time estimation in zebrafish (Danio rerio).
(Behav Processes, 2013-10)
Zebrafish were tested in an appetitive Pavlovian delayed conditioning task. After
an intertrial interval of k*T s (k=11.25; T=8, 16 or 32 s), a small, translucent vertical
pole was illuminated (CS) for T s. Food was presented ...
Heptahelical receptor signaling: beyond the G protein paradigm.
(J Cell Biol, 1999-05-31)
Rapid, accurate time estimation in zebrafish (Danio rerio).
(Behav Processes, 2013-10)
Zebrafish were tested in an appetitive Pavlovian delayed conditioning task. After
an intertrial interval of k*T s (k=11.25; T=8, 16 or 32 s), a small, translucent vertical
pole was illuminated (CS) for T s. Food was presented ...
A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
(Science (New York, N.Y.), 2005-02)
Most protein phosphatases have little intrinsic substrate specificity, making selective
pharmacological inhibition of specific dephosphorylation reactions a challenging problem.
In a screen for small molecules that protect ...
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
(Nature genetics, 2018-02)
Lipids, either endogenously synthesized or exogenous, have been linked to human cancer.
Here we found that PML is frequently co-deleted with PTEN in metastatic human prostate
cancer (CaP). We demonstrated that conditional ...
Preclinical and Coclinical Studies in Prostate Cancer.
(Cold Spring Harbor perspectives in medicine, 2018-04-02)
Men who develop metastatic castration-resistant prostate cancer (mCRPC) will invariably
succumb to their disease. Thus there remains a pressing need for preclinical testing
of new drugs and drug combinations for late-stage ...
Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models.
(The Journal of pathology, 2012-01)
Squamous metaplasia (SQM) is a specific phenotype in response to oestrogen in the
prostate and oestrogen receptor (ER) α is required to mediate this response. Previous
studies utilizing tissue recombination with seminal ...
Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis.
(Traffic (Copenhagen, Denmark), 2011-07)
Microglia are immune effector cells in the central nervous system (CNS) and their
activation, migration and proliferation play crucial roles in brain injuries and diseases.
We examined the role of intracellular ...