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Biogeography in deep time - What do phylogenetics, geology, and paleoclimate tell us about early platyrrhine evolution? 

Kay, Richard Frederick (Mol Phylogenet Evol, 2015-01)
Molecular data have converged on a consensus about the genus-level phylogeny of extant platyrrhine monkeys, but for most extinct taxa and certainly for those older than the Pleistocene we must rely upon morphological evidence ...
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Anthropology. New World monkey origins. 

Kay, Richard Frederick (Science, 2015-03-06)
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Rapid, accurate time estimation in zebrafish (Danio rerio). 

Cerutti, Daniel T; Jozefowiez, J; Staddon, John ER (Behav Processes, 2013-10)
Zebrafish were tested in an appetitive Pavlovian delayed conditioning task. After an intertrial interval of k*T s (k=11.25; T=8, 16 or 32 s), a small, translucent vertical pole was illuminated (CS) for T s. Food was presented ...
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Heptahelical receptor signaling: beyond the G protein paradigm. 

Hall, RA; Lefkowitz, Robert J; Premont, Richard Thomas (J Cell Biol, 1999-05-31)
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Rapid, accurate time estimation in zebrafish (Danio rerio). 

Cerutti, Daniel T; Jozefowiez, J; Staddon, John ER (Behav Processes, 2013-10)
Zebrafish were tested in an appetitive Pavlovian delayed conditioning task. After an intertrial interval of k*T s (k=11.25; T=8, 16 or 32 s), a small, translucent vertical pole was illuminated (CS) for T s. Food was presented ...
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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. 

Boyce, Michael; Bryant, Kevin F; Jousse, Céline; Long, Kai; Harding, Heather P; Scheuner, Donalyn; Kaufman, Randal J; ... (11 authors) (Science (New York, N.Y.), 2005-02)
Most protein phosphatases have little intrinsic substrate specificity, making selective pharmacological inhibition of specific dephosphorylation reactions a challenging problem. In a screen for small molecules that protect ...
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An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. 

Chen, Ming; Zhang, Jiangwen; Sampieri, Katia; Clohessy, John G; Mendez, Lourdes; Gonzalez-Billalabeitia, Enrique; Liu, Xue-Song; ... (23 authors) (Nature genetics, 2018-02)
Lipids, either endogenously synthesized or exogenous, have been linked to human cancer. Here we found that PML is frequently co-deleted with PTEN in metastatic human prostate cancer (CaP). We demonstrated that conditional ...
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Preclinical and Coclinical Studies in Prostate Cancer. 

Chen, Ming; Pandolfi, Pier Paolo (Cold Spring Harbor perspectives in medicine, 2018-04-02)
Men who develop metastatic castration-resistant prostate cancer (mCRPC) will invariably succumb to their disease. Thus there remains a pressing need for preclinical testing of new drugs and drug combinations for late-stage ...
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Loss of epithelial oestrogen receptor α inhibits oestrogen-stimulated prostate proliferation and squamous metaplasia via in vivo tissue selective knockout models. 

Chen, Ming; Yeh, Chiuan-Ren; Chang, Hong-Chiang; Vitkus, Spencer; Wen, Xing-Qiao; Bhowmick, Neil A; Wolfe, Andrew; ... (8 authors) (The Journal of pathology, 2012-01)
Squamous metaplasia (SQM) is a specific phenotype in response to oestrogen in the prostate and oestrogen receptor (ER) α is required to mediate this response. Previous studies utilizing tissue recombination with seminal ...
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Role of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis. 

Lee, Sang-Hyun; Schneider, Claus; Higdon, Ashlee N; Darley-Usmar, Victor M; Chung, Chang Y (Traffic (Copenhagen, Denmark), 2011-07)
Microglia are immune effector cells in the central nervous system (CNS) and their activation, migration and proliferation play crucial roles in brain injuries and diseases. We examined the role of intracellular ...
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AuthorJarvis, Erich D (65)Lefkowitz, RJ (62)Sheng, Huaxin (39)Sommer, Marc A (27)Brunel, Nicolas (24)Warner, David S (24)Caron, MG (22)Pimm, Stuart L (22)Field, Greg D (21)Koch, WJ (20)... View MoreDate Issued2020 - 2022 (55)2010 - 2019 (824)2000 - 2009 (183)1990 - 1999 (83)1980 - 1989 (24)1978 - 1979 (3)TypeJournal article (1168)Other article (4)Subject
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Humans (458)Mice (398)Male (281)Female (207)Mice, Inbred C57BL (133)Disease Models, Animal (110)Rats (108)Signal Transduction (108)Neurons (87)... View MoreAffiliation of Duke Author(s)Duke (1172)School of Medicine (923)Basic Science Departments (659)Clinical Science Departments (579)Institutes and Provost's Academic Units (453)Institutes and Centers (434)University Institutes and Centers (399)Duke Cancer Institute (373)Duke Institute for Brain Sciences (353)Trinity College of Arts & Sciences (332)... View More
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