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Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer.
(J Palliat Med, 2010-08)
BACKGROUND: Shared decision-making has become the standard of care for most medical
treatments. However, little is known about physician communication practices in the
decision making for unstable critically ill patients ...
Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials.
(J Altern Complement Med, 2010-10)
OBJECTIVES: Side-effects of standard pain medications can limit their use. Therefore,
nonpharmacologic pain relief techniques such as auriculotherapy may play an important
role in pain management. Our aim was to conduct ...
Dual-energy computed tomography with advanced postimage acquisition data processing: improved determination of urinary stone composition.
(J Endourol, 2010-03)
INTRODUCTION: The characterization of urinary calculi using noninvasive methods has
the potential to affect clinical management. CT remains the gold standard for diagnosis
of urinary calculi, but has not reliably differentiated ...
Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma.
(BMC Cancer, 2010-05-19)
BACKGROUND: Malignant glioma is a rare cancer with poor survival. The influence of
diet and antioxidant intake on glioma survival is not well understood. The current
study examines the association between antioxidant intake ...
Ligation of cell surface GRP78 with antibody directed against the COOH-terminal domain of GRP78 suppresses Ras/MAPK and PI 3-kinase/AKT signaling while promoting caspase activation in human prostate cancer cells.
(Cancer Biol Ther, 2010-01)
We have previously shown that treatment of prostate cancer and melanoma cells expressing
GRP78 on their cell surface with antibody directed against the COOH-terminal domain
of GRP78 upregulates and activates p53 causing ...
Quality control autophagy: a joint effort of ubiquitin, protein deacetylase and actin cytoskeleton.
(Autophagy, 2010-05)
Autophagy has been predominantly studied as a nonselective self-digestion process
that recycles macromolecules and produces energy in response to starvation. However,
autophagy independent of nutrient status has long been ...
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
(Autophagy, 2010-02)
VCP (VCP/p97) is a ubiquitously expressed member of the AAA(+)-ATPase family of chaperone-like
proteins that regulates numerous cellular processes including chromatin decondensation,
homotypic membrane fusion and ...
Detection of depression in low resource settings: validation of the Patient Health Questionnaire (PHQ-9) and cultural concepts of distress in Nepal.
(BMC Psychiatry, 2016-03-08)
BACKGROUND: Despite recognition of the burden of disease due to mood disorders in
low- and middle-income countries, there is a lack of consensus on best practices for
detecting depression. Self-report screening tools, such ...
The influence of hepatic function on prostate cancer outcomes after radical prostatectomy.
(Prostate Cancer Prostatic Dis, 2010-06)
Prostate growth is dependent on circulating androgens, which can be influenced by
hepatic function. Liver disease has been suggested to influence prostate cancer (CaP)
incidence. However, the effect of hepatic function on ...
The genomic analysis of erythrocyte microRNA expression in sickle cell diseases.
(PLoS One, 2008-06-04)
BACKGROUND: Since mature erythrocytes are terminally differentiated cells without
nuclei and organelles, it is commonly thought that they do not contain nucleic acids.
In this study, we have re-examined this issue by analyzing ...