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Now showing items 1-10 of 2140
The Color of COVID-19: Structural Racism and the Disproportionate Impact of the Pandemic on Older Black and Latinx Adults.
(The journals of gerontology. Series B, Psychological sciences and social sciences, 2021-02)
<h4>Objectives</h4>The aim of this evidence-based theoretically informed article was
to provide an overview of how and why the COVID-19 outbreak is particularly detrimental
for the health of older Black and Latinx ...
Bone Marrow Mesenchymal Stem Cell Transplantation Increases GAP-43 Expression via ERK1/2 and PI3K/Akt Pathways in Intracerebral Hemorrhage.
(Cellular physiology and biochemistry : international journal of experimental cellular
physiology, biochemistry, and pharmacology, 2017-01)
<h4>Background/aims</h4>Intracerebral hemorrhage (ICH) occurs in hypertensive patients
and results in high rates of mortality and disability. This study determined whether
bone marrow mesenchymal stem cell (BMSC) transplantation ...
Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.
(Kidney Int, 2014-12)
Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes,
including inherited genetic defects, with significant proteinuria being the predominant
clinical finding at presentation. Mutations in ...
Stimulus dependence of local field potential spectra: experiment versus theory.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-10)
The local field potential (LFP) captures different neural processes, including integrative
synaptic dynamics that cannot be observed by measuring only the spiking activity of
small populations. Therefore, investigating how ...
A cerebellar learning model of vestibulo-ocular reflex adaptation in wild-type and mutant mice.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-05)
Mechanisms of cerebellar motor learning are still poorly understood. The standard
Marr-Albus-Ito theory posits that learning involves plasticity at the parallel fiber
to Purkinje cell synapses under control of the climbing ...
Neuronal morphology generates high-frequency firing resonance.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015-05)
The attenuation of neuronal voltage responses to high-frequency current inputs by
the membrane capacitance is believed to limit single-cell bandwidth. However, neuronal
populations subject to stochastic fluctuations can ...
Inhibition stabilization is a widespread property of cortical networks.
(eLife, 2020-06-29)
Many cortical network models use recurrent coupling strong enough to require inhibition
for stabilization. Yet it has been experimentally unclear whether inhibition-stabilized
network (ISN) models describe cortical function ...
A phase I study of ABT-510 plus bevacizumab in advanced solid tumors.
(Cancer Med, 2013-06)
Targeting multiple regulators of tumor angiogenesis have the potential to improve
treatment efficacy. Bevacizumab is a monoclonal antibody directed against vascular
endothelial growth factor and ABT-510 is a synthetic analog ...
Acetylcholine Modulates Cerebellar Granule Cell Spiking by Regulating the Balance of Synaptic Excitation and Inhibition.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020-04)
Sensorimotor integration in the cerebellum is essential for refining motor output,
and the first stage of this processing occurs in the granule cell layer. Recent evidence
suggests that granule cell layer synaptic integration ...
Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings.
(J Neurosci, 2015-03-18)
This study combines for the first time two major approaches to understanding the function
and structure of neural circuits: large-scale multielectrode recordings, and confocal
imaging of labeled neurons. To achieve this ...