Now showing items 1-10 of 393
Detection of depression in low resource settings: validation of the Patient Health Questionnaire (PHQ-9) and cultural concepts of distress in Nepal.
(BMC Psychiatry, 2016-03-08)
BACKGROUND: Despite recognition of the burden of disease due to mood disorders in low- and middle-income countries, there is a lack of consensus on best practices for detecting depression. Self-report screening tools, such ...
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
(Subst Abuse Treat Prev Policy, 2012-03-20)
BACKGROUND: Although methadone has been used for the maintenance treatment of opioid dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug interactions (MDIs) have been shown to cause ...
Studying human fertility and environmental exposures.
(Environ Health Perspect, 2004-08)
Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection.
(PLoS One, 2015)
Although neuroanatomical tracing studies have defined the origin and targets of major projection neurons (PN) of the central nervous system (CNS), there is much less information about the circuits that influence these neurons. ...
Age mediation of frontoparietal activation during visual feature search.
Activation of frontal and parietal brain regions is associated with attentional control during visual search. We used fMRI to characterize age-related differences in frontoparietal activation in a highly efficient feature ...
Differences in the early cognitive development of children and great apes.
(Dev Psychobiol, 2014-04)
There is very little research comparing great ape and human cognition developmentally. In the current studies we compared a cross-sectional sample of 2- to 4-year-old human children (n=48) with a large sample of chimpanzees ...
Direct and indirect reputation formation in nonhuman great apes (Pan paniscus, Pan troglodytes, Gorilla gorilla, Pongo pygmaeus) and human children (Homo sapiens).
(J Comp Psychol, 2013-02)
Humans make decisions about when and with whom to cooperate based on their reputations. People either learn about others by direct interaction or by observing third-party interactions or gossip. An important question is ...
A comparison of temperament in nonhuman apes and human infants.
(Dev Sci, 2011-11)
The adaptive behavior of primates, including humans, is often mediated by temperament. Human behavior likely differs from that of other primates in part due to temperament. In the current study we compared the reaction of ...
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.
(J Clin Invest, 2010-05)
The folate pathway plays a crucial role in the regeneration and repair of the adult CNS after injury. Here, we have shown in rodents that such repair occurs at least in part through DNA methylation. In animals with combined ...
The architecture of cross-hemispheric communication in the aging brain: linking behavior to functional and structural connectivity.
(Cereb Cortex, 2012-01)
Contralateral recruitment remains a controversial phenomenon in both the clinical and normative populations. To investigate the neural correlates of this phenomenon, we explored the tendency for older adults to recruit prefrontal ...