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Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults.
(The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2011-10)
Based on the multiple logistic regression analysis of data from a random sample of
1,023 old adults collected in Taiwan in 2000, we found that interactions between carrying
the APOE4 allele and one of four life stress factors ...
A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.
(PloS one, 2014-01)
Psychosocial stress is well known to be positively associated with subsequent depressive
symptoms. Cortisol response to stress may be one of a number of biological mechanisms
that links psychological stress to depressive ...
An Initial Evaluation of the Impact of Pokémon GO on Physical Activity.
(Journal of the American Heart Association, 2017-05-16)
Pokémon GO is a location-based augmented reality game. Using GPS and the camera on
a smartphone, the game requires players to travel in real world to capture animated
creatures, called Pokémon. We examined the impact of ...
The Digital Drag and Drop Pillbox: Design and Feasibility of a Skill-based Education Model to Improve Medication Management.
(The Journal of cardiovascular nursing, 2017-09)
We present the design and feasibility testing for the "Digital Drag and Drop Pillbox"
(D-3 Pillbox), a skill-based educational approach that engages patients and providers,
measures performance, and generates reports of ...
TNFRSF1B +676 T>G polymorphism predicts survival of non-small cell lung cancer patients treated with chemoradiotherapy.
(BMC cancer, 2011-10-14)
The dysregulation of gene expression in the TNF-TNFR superfamily has been involved
in various human cancers including non-small cell lung cancer (NSCLC). Furthermore,
functional polymorphisms in TNF-α and TNFRSF1B genes ...
Serum N-propeptide of collagen IIA (PIIANP) as a marker of radiographic osteoarthritis burden.
(PloS one, 2017-01)
Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage
matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum
levels of type IIA procollagen amino terminal propeptide ...
Correlation between base-excision repair gene polymorphisms and levels of in-vitro BPDE-induced DNA adducts in cultured peripheral blood lymphocytes.
(PloS one, 2012-01)
In vitro benzo[a]pyrene diol epoxide (BPDE)-induced DNA adducts in cultured peripheral
lymphocytes have been shown to be a phenotypic biomarker of individual's DNA repair
phenotype that is associated with cancer risk. In ...
Dietary Patterns Associated with Cognitive Function among the Older People in Underdeveloped Regions: Finding from the NCDFaC Study.
(Nutrients, 2018-04-09)
Although dietary patterns are crucial to cognitive function, associations of dietary
patterns with cognitive function have not yet been fully understood. This cross-sectional
study explored dietary patterns associated with ...
Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men.
(Asian journal of andrology, 2014-11)
Adiponectin secreted by adipose tissue has been implicated in prostate carcinogenesis.
Genetic variations in ADIPOQ are thought to influence the activity of adiponectin,
thus relating to cancer occurrence. In this hospital-based ...
Association of combined p73 and p53 genetic variants with tumor HPV16-positive oropharyngeal cancer.
(PloS one, 2012-01)
p53 and p73 interact with human papillomavirus (HPV) E6 and E7 oncoproteins. The interplay
between p53 and p73 and HPV16 may lead to deregulation of cell cycle and apoptosis,
through which inflammation/immune responses control ...