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    Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. 

    Cao, L; Fermor, B; Griffin, TM; Guilak, Farshid; Huebner, JL; Kraus, Virginia Byers; Rodriguiz, Ramona M; ... (9 authors) (Arthritis Res Ther, 2010)
    INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ...
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    Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis. 

    Adams, SB; Allen, Kyle D; Gabr, Mostafa A; Huebner, JL; Kraus, Virginia Byers; Mata, BA; Schmitt, Daniel Oliver; ... (8 authors) (Arthritis Res Ther, 2012-04-17)
    INTRODUCTION: Osteoarthritis (OA) results in pain and disability; however, preclinical OA models often focus on joint-level changes. Gait analysis is one method used to evaluate both preclinical OA models and OA patients. ...
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    Progress in intra-articular therapy. 

    Evans, CH; Kraus, Virginia Byers; Setton, Lori A (Nat Rev Rheumatol, 2014-01)
    Diarthrodial joints are well suited to intra-articular injection, and the local delivery of therapeutics in this fashion brings several potential advantages to the treatment of a wide range of arthropathies. Possible benefits ...
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    Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice 

    Cao, L; Fermor, B; Griffin, TM; Guilak, Farshid; Huebner, JL; Kraus, Virginia Byers; Rodriguiz, Ramona M; ... (9 authors) (ARTHRITIS RESEARCH & THERAPY, 2010)
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    In Vivo luminescent imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. 

    Bell, RD; Bowles, RD; Huebner, JL; Kraus, Virginia Byers; Mata, BA; Mwangi, TK; Setton, Lori A (Arthritis Rheum, 2013-11-18)
    Objective: To investigate the relationship between NF-κB activity, cytokine levels, and pain sensitivities in a rodent model of osteoarthritis (OA). Method: OA was induced in transgenic NF-κB luciferase reporter mice via ...
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    Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy. 

    Allen, Kyle D; Gabr, Mostafa A; Huebner, JL; Hwang, PY; Jing, L; Kraus, Virginia Byers; Mata, BA; ... (10 authors) (Open Orthop J, 2012)
    Intervertebral disc herniation may contribute to inflammatory processes that associate with radicular pain and motor deficits. Molecular changes at the affected dorsal root ganglion (DRG), spinal cord, and even midbrain, ...
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    In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. 

    Bell, RD; Bowles, RD; Huebner, JL; Kraus, Virginia Byers; Mata, BA; Mwangi, TK; Setton, Lori A (Arthritis Rheumatol, 2014-03)
    OBJECTIVE: To investigate the relationship between NF-κB activity, cytokine levels, and pain sensitivities in a rodent model of osteoarthritis (OA). METHODS: OA was induced in transgenic NF-κB-luciferase reporter mice via ...
     

     

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    Author
    Kraus, Virginia Byers (7)
    Setton, Lori A (7)
    Huebner, JL (6)Mata, BA (4)Allen, Kyle D (2)Bell, RD (2)Bowles, RD (2)Cao, L (2)Fermor, B (2)Gabr, Mostafa A (2)... View MoreDate Issued2010 (2)2012 (2)2014 (2)2013 (1)TypeJournal article (7)SubjectAnimals (3)Mice (2)Osteoarthritis, Knee (2)Adaptation, Physiological (1)Adipokines (1)Adrenal Cortex Hormones (1)Anti-Inflammatory Agents, Non-Steroidal (1)Antirheumatic Agents (1)Arthritis, Experimental (1)Behavior, Animal (1)... View MoreAffiliation of Duke Author(s)Biomedical Engineering (7)Clinical Science Departments (7)Duke (7)Duke Institute for Brain Sciences (7)
    Duke Molecular Physiology Institute (7)
    Institutes and Centers (7)Institutes and Provost's Academic Units (7)
    Medicine (7)
    Medicine, Rheumatology and Immunology (7)
    Orthopaedics (7)... View More