Now showing items 1-3 of 3
Determinants of protection among HIV‐exposed seronegative persons: an overview.
(J Infect Dis, 2010-11-01)
Both clinical experience and a growing medical literature indicate that some persons who have been exposed to human immunodeficiency virus (HIV) infection remain uninfected. Although in some instances this may represent ...
Screening the human exome: a comparison of whole genome and whole transcriptome sequencing.
(Genome Biol, 2010)
BACKGROUND: There is considerable interest in the development of methods to efficiently identify all coding variants present in large sample sets of humans. There are three approaches possible: whole-genome sequencing, ...
The characterization of twenty sequenced human genomes.
(PLoS Genet, 2010-09-09)
We present the analysis of twenty human genomes to evaluate the prospects for identifying rare functional variants that contribute to a phenotype of interest. We sequenced at high coverage ten "case" genomes from individuals ...