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Now showing items 1-10 of 12
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Variability in the treatment of elderly patients with stage IIIA (N2) non-small-cell lung cancer.
(J Thorac Oncol, 2013-06)
INTRODUCTION: : We evaluated treatment patterns of elderly patients with stage IIIA
(N2) non-small-cell lung cancer (NSCLC). METHODS: : The use of surgery, chemotherapy,
and radiation for patients with stage IIIA (T1-T3N2M0) ...
Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.
(J Thorac Cardiovasc Surg, 2014-04)
OBJECTIVE: Recently, the role of β-blockers (BBs) in reducing perioperative mortality
has been challenged. The conflicting results might have resulted from the extent of
BB metabolism by the cytochrome P-450 (CYP2D6) isoenzyme. ...
Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms.
(Breast Cancer Res Treat, 2011-07)
The observed bimodal patterns of breast cancer incidence in the U.S. suggested that
breast cancer may be viewed as more than one biological entity. We studied the factors
potentially contributing to this phenomenon, specifically ...
Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients.
(Ann Surg Oncol, 2015-02)
BACKGROUND: We evaluated the use and efficacy of adjuvant chemotherapy after resection
of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS: Factors
associated with the use of adjuvant chemotherapy ...
Medical cost trajectories and onsets of cancer and noncancer diseases in US elderly population.
(Comput Math Methods Med, 2011)
Time trajectories of medical costs-associated with onset of twelve aging-related cancer
and chronic noncancer diseases were analyzed using the National Long-Term Care Survey
data linked to Medicare Service Use files. A special ...
Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.
(Lung Cancer, 2017-06-05)
OBJECTIVES: To evaluate the role of cardiovascular disease (CVD) comorbidity in survival
of patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: The impact
of seven CVDs (at the time of NSCLC diagnosis ...
Causal effects of time-dependent treatments in older patients with non-small cell lung cancer.
(PLoS One, 2015)
BACKGROUND: Treatment selection for elderly patients with lung cancer must balance
the benefits of curative/life-prolonging therapy and the risks of increased mortality
due to comorbidities. Lung cancer trials generally ...
Evaluating the number of stages in development of squamous cell and adenocarcinomas across cancer sites using human population-based cancer modeling.
(PLoS One, 2012)
BACKGROUND: Adenocarcinomas (ACs) and squamous cell carcinomas (SCCs) differ by clinical
and molecular characteristics. We evaluated the characteristics of carcinogenesis
by modeling the age patterns of incidence rates of ...
Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis.
(J Am Geriatr Soc, 2012-02)
OBJECTIVES: To use the Medicare Files of Service Use (MFSU) to evaluate patterns in
the incidence of aging-related diseases in the U.S. elderly population. DESIGN: Age-specific
incidence rates of 19 aging-related diseases ...