Now showing items 1-10 of 10
Mapping nonlinear receptive field structure in primate retina at single cone resolution.
The function of a neural circuit is shaped by the computations performed by its interneurons, which in many cases are not easily accessible to experimental investigation. Here, we elucidate the transformation of visual signals ...
A polyaxonal amacrine cell population in the primate retina.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-03)
Amacrine cells are the most diverse and least understood cell class in the retina. Polyaxonal amacrine cells (PACs) are a unique subset identified by multiple long axonal processes. To explore their functional properties, ...
Efficient coding of spatial information in the primate retina.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012-11)
Sensory neurons have been hypothesized to efficiently encode signals from the natural environment subject to resource constraints. The predictions of this efficient coding hypothesis regarding the spatial filtering properties ...
Retinal Representation of the Elementary Visual Signal
Retinal representation of the elementary visual signal.
The propagation of visual signals from individual cone photoreceptors through parallel neural circuits was examined in the primate retina. Targeted stimulation of individual cones was combined with simultaneous recording ...
Correlated firing among major ganglion cell types in primate retina.
(The Journal of physiology, 2011-01)
Retinal ganglion cells exhibit substantial correlated firing: a tendency to fire nearly synchronously at rates different from those expected by chance. These correlations suggest that network interactions significantly shape ...
Identification of a Retinal Circuit for Recurrent Suppression Using Indirect Electrical Imaging.
(Current biology : CB, 2016-08)
Understanding the function of modulatory interneuron networks is a major challenge, because such networks typically operate over long spatial scales and involve many neurons of different types. Here, we use an indirect electrical ...
Functional connectivity in the retina at the resolution of photoreceptors.
To understand a neural circuit requires knowledge of its connectivity. Here we report measurements of functional connectivity between the input and ouput layers of the macaque retina at single-cell resolution and the implications ...
Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings.
(J Neurosci, 2015-03-18)
This study combines for the first time two major approaches to understanding the function and structure of neural circuits: large-scale multielectrode recordings, and confocal imaging of labeled neurons. To achieve this ...
High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina.
(Nat Neurosci, 2009-09)
Small bistratified cells (SBCs) in the primate retina carry a major blue-yellow opponent signal to the brain. We found that SBCs also carry signals from rod photoreceptors, with the same sign as S cone input. SBCs exhibited ...