Now showing items 1-4 of 4
Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact.
A common strategy by which developing neurons locate their synaptic partners is through projections to circuit-specific neuropil sublayers. Once established, sublayers serve as a substrate for selective synapse formation, ...
Temporal resolution of single photon responses in primate rod photoreceptors and limits imposed by cellular noise.
(Journal of neurophysiology, 2018-11-28)
Sensory receptor noise corrupts sensory signals, contributing to imperfect perception and dictating central processing strategies. For example, noise in rod phototransduction limits our ability to detect light and minimizing ...
Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells.
Direction-selective ganglion cells (DSGCs) deliver signals from the retina to multiple brain areas to indicate the presence and direction of motion. Delivering reliable signals in response to motion is critical across light ...
Nogo receptor 1 is expressed by nearly all retinal ganglion cells.
(PloS one, 2018-01)
A variety of conditions ranging from glaucoma to blunt force trauma lead to optic nerve atrophy. Identifying signaling pathways for stimulating axon growth in the optic nerve may lead to treatments for these pathologies. ...