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Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients.

Akushevich, Igor; Berry, Mark Francis; Coleman, BK; Curtis, Lesley H; D'Amico, Thomas Anthony; Worni, Mathias (Ann Surg Oncol, 2015-02)

BACKGROUND: We evaluated the use and efficacy of adjuvant chemotherapy after resection of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS: Factors associated with the use of adjuvant chemotherapy ...

Causal effects of time-dependent treatments in older patients with non-small cell lung cancer.

Akushevich, Igor; Arbeev, Konstantin; Kravchenko, J; Berry, Mark Francis (PLoS One, 2015)

BACKGROUND: Treatment selection for elderly patients with lung cancer must balance the benefits of curative/life-prolonging therapy and the risks of increased mortality due to comorbidities. Lung cancer trials generally ...