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Staying cool when things get hot: emotion regulation modulates neural mechanisms of memory encoding.
(Front Hum Neurosci, 2010)
During times of emotional stress, individuals often engage in emotion regulation to
reduce the experiential and physiological impact of negative emotions. Interestingly,
emotion regulation strategies also influence memory ...
Effects of chronic mild traumatic brain injury on white matter integrity in iraq and afghanistan war veterans
(Human Brain Mapping, 2013-11-01)
Mild traumatic brain injury (TBI) is a common source of morbidity from the wars in
Iraq and Afghanistan. With no overt lesions on structural MRI, diagnosis of chronic
mild TBI in military veterans relies on obtaining an ...
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.
(Transl Psychiatry, 2015-12-15)
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event,
differing on a variety of sensory and affective ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Scan-rescan reliability of subcortical brain volumes derived from automated segmentation.
(Hum Brain Mapp, 2010-11)
Large-scale longitudinal studies of regional brain volume require reliable quantification
using automated segmentation and labeling. However, repeated MR scanning of the same
subject, even if using the same scanner ...
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.
(Arch Gen Psychiatry, 2012-11)
CONTEXT: Smaller hippocampal volumes are well established in posttraumatic stress
disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced
equivocal results. OBJECTIVE: To assess a large cohort ...
Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD.
(J Psychiatr Res, 2011-05)
Neurobiological models of posttraumatic stress disorder (PTSD) suggest that altered
activity in the medial temporal lobes (MTL) during encoding of traumatic memories
contribute to the development and maintenance of the disorder. ...
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans,
many of whom continue to experience persistent pain symptoms despite multiple pharmacological
interventions. Preclinical data suggest ...
Altered resting-state functional connectivity of basolateral and centromedial amygdala complexes in posttraumatic stress disorder.
(Neuropsychopharmacology, 2014-01)
The amygdala is a major structure that orchestrates defensive reactions to environmental
threats and is implicated in hypervigilance and symptoms of heightened arousal in
posttraumatic stress disorder (PTSD). The basolateral ...
Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.
(BMC Psychiatry, 2011-05-05)
BACKGROUND: Serotonergic system dysfunction has been implicated in posttraumatic stress
disorder (PTSD). Genetic polymorphisms associated with serotonin signaling may predict
differences in brain circuitry involved in emotion ...