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    cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor. 

    Bolanowski, MA; Caron, MG; Dixon, RA; Dohlman, HG; Francke, U; Frielle, T; Kobilka, BK; ... (10 authors) (Proc Natl Acad Sci U S A, 1987-01)
    We have isolated and sequenced a cDNA encoding the human beta 2-adrenergic receptor. The deduced amino acid sequence (413 residues) is that of a protein containing seven clusters of hydrophobic amino acids suggestive of ...
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    Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein). 

    Benovic, JL; Caron, MG; Codina, J; Kühn, H; Lefkowitz, Robert J; Weyand, I (Proc Natl Acad Sci U S A, 1987-12)
    The beta-adrenergic receptor kinase is an enzyme, possibly analogous to rhodopsin kinase, that multiply phosphorylates the beta-adrenergic receptor only when it is occupied by stimulatory agonists. Since this kinase may ...
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    Cloning of the cDNA for the human beta 1-adrenergic receptor. 

    Caron, MG; Collins, Sheila; Daniel, KW; Frielle, T; Kobilka, BK; Lefkowitz, Robert J (Proc Natl Acad Sci U S A, 1987-11)
    Screening of a human placenta lambda gt11 library has led to the isolation of the cDNA for the human beta 1-adrenergic receptor (beta 1AR). Used as the probe was the human genomic clone termed G-21. This clone, which contains ...
     

     

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    AuthorCaron, MG (3)
    Lefkowitz, Robert J (3)
    Frielle, T (2)Kobilka, BK (2)Benovic, JL (1)Bolanowski, MA (1)Codina, J (1)Collins, Sheila (1)Daniel, KW (1)Dixon, RA (1)... View MoreDate Issued
    1987 (3)
    TypeJournal article (3)SubjectAnimals (3)
    Humans (3)
    Receptors, Adrenergic, beta (3)Amino Acid Sequence (2)Base Sequence (2)DNA (2)Antigens (1)Arrestin (1)beta-Adrenergic Receptor Kinases (1)Cell Membrane (1)... View MoreAffiliation of Duke Author(s)Basic Science Departments (3)Biochemistry (3)Cell Biology (3)Chemistry (3)
    Clinical Science Departments (3)
    Duke (3)Duke Cancer Institute (3)Duke Institute for Brain Sciences (3)Institutes and Centers (3)Institutes and Provost's Academic Units (3)... View More