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    Enhanced myocardial relaxation in vivo in transgenic mice overexpressing the beta2-adrenergic receptor is associated with reduced phospholamban protein. 

    Hamilton, RA; Jones, LR; Lefkowitz, Robert J; Mao, L; Milano, Carmelo Alessio; Rockman, Howard A (J Clin Invest, 1996-04-01)
    To assess the effect of targeted myocardial beta-adrenergic receptor (AR) stimulation on relaxation and phospholamban regulation, we studied the physiological and biochemical alterations associated with overexpression of ...
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    Localisation of [131I]MIBG in nude mice bearing SK-N-SH human neuroblastoma xenografts: effect of specific activity. 

    Friedman, HS; Keir, ST; Vaidyanathan, Ganesan; Zalutsky, Michael Rod (Br J Cancer, 1996-05)
    The biodistribution of no-carrier-added (n.c.a.) meta-[131I]iodobenzylguanidine ([131I]MIBG) and that prepared by the standard isotopic exchange method were compared in athymic mice bearing SK-N-SH human neuroblastoma xenografts. ...
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    Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. 

    Diversé-Pierluissi, M; Drazner, Mark H; Dyer, SL; Freedman, NJ; Lefkowitz, Robert J; Oppermann, M; Peppel, Karsten C (Proc Natl Acad Sci U S A, 1996-07-23)
    Guanine nucleotide-binding regulatory protein (G protein)-coupled receptor kinases (GRKs) constitute a family of serine/threonine kinases that play a major role in the agonist-induced phosphorylation and desensitization ...
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    Mitogenic signaling via G protein-coupled receptors. 

    Hawes, BE; Lefkowitz, Robert J; Luttrell, LM; van Biesen, T (Endocr Rev, 1996-12)
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    The third beta is not the charm. 

    Bond, RA; Lefkowitz, Robert J (J Clin Invest, 1996-07-15)
     

     

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    AuthorLefkowitz, Robert J (4)Bond, RA (1)Diversé-Pierluissi, M (1)Drazner, Mark H (1)Dyer, SL (1)Freedman, NJ (1)Friedman, HS (1)Hamilton, RA (1)Hawes, BE (1)Jones, LR (1)... View MoreDate Issued
    1996 (5)
    TypeJournal article (5)Subject
    Humans (5)
    Animals (4)GTP-Binding Proteins (3)Heart (2)Mice (2)Myocardial Contraction (2)Myocardium (2)Receptors, Adrenergic, beta-2 (2)Receptors, Cell Surface (2)3-Iodobenzylguanidine (1)... View MoreAffiliation of Duke Author(s)Clinical Science Departments (5)Duke (5)Duke Cancer Institute (5)Institutes and Centers (5)
    Medicine (5)
    Pathology (5)
    School of Medicine (5)
    Basic Science Departments (4)Biochemistry (4)Chemistry (4)... View More