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Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.
(Kidney Int, 2014-12)
Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes,
including inherited genetic defects, with significant proteinuria being the predominant
clinical finding at presentation. Mutations in ...
Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.
(Int J Chron Obstruct Pulmon Dis, 2014)
BACKGROUND: The respiratory tract is a major target of exposure to air pollutants,
and respiratory diseases are associated with both short- and long-term exposures.
We hypothesized that improved air quality in North Carolina ...
Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise.
(Journal of cardiovascular translational research, 2014-04)
Despite the significant progress that has been made in identifying disease-associated
mutations, the utility of the hypertrophic cardiomyopathy (HCM) genetic test is limited
by a lack of understanding of the background genetic ...
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.
(Journal of neuropathology and experimental neurology, 2011-04)
Mutations in dysferlin cause an inherited muscular dystrophy because of defective
membrane repair. Three interacting partners of dysferlin are also implicated in membrane
resealing: caveolin-3 (in limb girdle muscular dystrophy ...
Awareness of Cervical Cancer Causes and Predeterminants of Likelihood to Screen Among Women in Haiti.
(Journal of lower genital tract disease, 2017-01)
Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given
this high disease burden, we sought to better understand women's knowledge of its
causes and the sociodemographic and health correlates of ...
Child welfare agency ties to providers and schools and substance abuse treatment use by adolescents.
(Journal of substance abuse treatment, 2011-01)
Policy makers and advocates are increasingly encouraging child-serving organizations
to work together. This study examined how child welfare agency ties with substance
abuse treatment providers and schools correlated with ...
Use of Salvia divinorum in a nationally representative sample.
(The American journal of drug and alcohol abuse, 2012-01)
Salvia divinorum has known hallucinogenic effects and is legal in most parts of the
United States. Given that this psychoactive substance has a potential of misuse and
abuse, further data regarding the clinical and psychosocial ...
Impact of coverage-dependent marginal costs on optimal HPV vaccination strategies.
(Epidemics, 2015-06)
The effectiveness of vaccinating males against the human papillomavirus (HPV) remains
a controversial subject. Many existing studies conclude that increasing female coverage
is more effective than diverting resources into ...
Mental Health and Substance Use Among Patients in a North Carolina HIV Clinic.
(N C Med J, 2015-07)
BACKGROUND: The HIV/AIDS epidemic is a significant public health concern in North
Carolina, and previous research has pointed to elevated mental health distress and
substance use among HIV-infected populations, which may ...