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The Color of COVID-19: Structural Racism and the Disproportionate Impact of the Pandemic on Older Black and Latinx Adults.
(The journals of gerontology. Series B, Psychological sciences and social sciences, 2021-02)
<h4>Objectives</h4>The aim of this evidence-based theoretically informed article was
to provide an overview of how and why the COVID-19 outbreak is particularly detrimental
for the health of older Black and Latinx ...
Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis.
(Kidney Int, 2014-12)
Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes,
including inherited genetic defects, with significant proteinuria being the predominant
clinical finding at presentation. Mutations in ...
Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.
(Int J Chron Obstruct Pulmon Dis, 2014)
BACKGROUND: The respiratory tract is a major target of exposure to air pollutants,
and respiratory diseases are associated with both short- and long-term exposures.
We hypothesized that improved air quality in North Carolina ...
Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise.
(Journal of cardiovascular translational research, 2014-04)
Despite the significant progress that has been made in identifying disease-associated
mutations, the utility of the hypertrophic cardiomyopathy (HCM) genetic test is limited
by a lack of understanding of the background genetic ...
Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch.
(Journal of neuropathology and experimental neurology, 2011-04)
Mutations in dysferlin cause an inherited muscular dystrophy because of defective
membrane repair. Three interacting partners of dysferlin are also implicated in membrane
resealing: caveolin-3 (in limb girdle muscular dystrophy ...
Awareness of Cervical Cancer Causes and Predeterminants of Likelihood to Screen Among Women in Haiti.
(Journal of lower genital tract disease, 2017-01)
Cervical cancer is the leading cause of cancer deaths among women in Haiti. Given
this high disease burden, we sought to better understand women's knowledge of its
causes and the sociodemographic and health correlates of ...
Mental Health and Substance Use Among Patients in a North Carolina HIV Clinic.
(N C Med J, 2015-07)
BACKGROUND: The HIV/AIDS epidemic is a significant public health concern in North
Carolina, and previous research has pointed to elevated mental health distress and
substance use among HIV-infected populations, which may ...
Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection.
(PLoS Genet, 2011-08)
Exposure to influenza viruses is necessary, but not sufficient, for healthy human
hosts to develop symptomatic illness. The host response is an important determinant
of disease progression. In order to delineate host molecular ...
Antibiotic overuse for acute respiratory tract infections in Sri Lanka: a qualitative study of outpatients and their physicians.
(BMC Fam Pract, 2018-03-01)
BACKGROUND: Acute respiratory tract infections (ARTIs) are a common reason for antibiotic
overuse worldwide. We previously showed that over 80% of outpatients presenting to
a tertiary care hospital in Sri Lanka ...
Chikungunya as a cause of acute febrile illness in southern Sri Lanka.
(PLoS One, 2013)
BACKGROUND: Chikungunya virus (CHIKV) re-emerged in Sri Lanka in late 2006 after a
40-year hiatus. We sought to identify and characterize acute chikungunya infection
(CHIK) in patients presenting with acute undifferentiated ...