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A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.
(PloS one, 2014-01)
Psychosocial stress is well known to be positively associated with subsequent depressive
symptoms. Cortisol response to stress may be one of a number of biological mechanisms
that links psychological stress to depressive ...
Personal DNA testing in college classrooms: perspectives of students and professors.
(Genetic testing and molecular biomarkers, 2013-06)
Discourse on the integration of personal genetics and genomics into classrooms is
increasing; however, limited data have been collected on the perspectives of students
and professors. We conducted a cross-sectional survey ...
A craniofacial-specific monosynaptic circuit enables heightened affective pain.
(Nature neuroscience, 2017-12)
Humans often rank craniofacial pain as more severe than body pain. Evidence suggests
that a stimulus of the same intensity induces stronger pain in the face than in the
body. However, the underlying neural circuitry for ...
Psychometric properties of the osteoporosis assessment questionnaire (OPAQ) 2.0: results from the multiple outcomes of raloxifene evaluation (MORE) study.
(BMC musculoskeletal disorders, 2014-01)
BACKGROUND: We explored psychometric properties of the Osteoporosis Assessment Questionnaire
2.0 in terms of reliability, validity, and responsiveness with generic, clinical,
demographic, and preference-based data collected ...
Strategic allocation of attention reduces temporally predictable stimulus conflict.
(J Cogn Neurosci, 2012-09)
Humans are able to continuously monitor environmental situations and adjust their
behavioral strategies to optimize performance. Here we investigate the behavioral
and brain adjustments that occur when conflicting stimulus ...
"I Use Weed for My ADHD": A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD.
(PLoS One, 2016)
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a risk factor for problematic
cannabis use. However, clinical and anecdotal evidence suggest an increasingly popular
perception that cannabis is therapeutic ...
PhenX RISING: real world implementation and sharing of PhenX measures.
(BMC Med Genomics, 2014-03-20)
BACKGROUND: The purpose of this manuscript is to describe the PhenX RISING network
and the site experiences in the implementation of PhenX measures into ongoing population-based
genomic studies. METHODS: Eighty PhenX measures ...
The dynamics of proactive and reactive cognitive control processes in the human brain.
(J Cogn Neurosci, 2014-05)
In this study, we leveraged the high temporal resolution of EEG to examine the neural
mechanisms underlying the flexible regulation of cognitive control that unfolds over
different timescales. We measured behavioral and ...
Recovery and survival from aging-associated diseases.
(Exp Gerontol, 2013-08)
OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan
of the US elderly population may lead to erroneous conclusions when recovery/long-term
remission factors are underestimated. Using two ...
Steps to Health employee weight management randomized control trial: short-term follow-up results.
(J Occup Environ Med, 2015-02)
OBJECTIVE: To present the short-term follow-up findings of the Steps to Health study,
a randomized trial to evaluate the effectiveness of two employee weight management
programs offered within Duke University and the Health ...