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    CASP7 variants modify susceptibility to cervical cancer in Chinese women. 

    Wei, Qingyi; Shi, Ting-Yan; He, Jing; Wang, Meng-Yun; Zhu, Mei-Ling; Yu, Ke-Da; Shao, Zhi-Ming; ... (10 authors) (Scientific reports, 2015-01)
    Polymorphisms in Caspase-7 (CASP7) may modulate the programmed cell death and thus contribute to cervical cancer risk. In this case-control study of 1,486 cervical cancer cases and 1,301 controls, we investigated associations ...
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    Genetic variations of the ADIPOQgene and risk of prostate cancer in Chinese Han men. 

    Wei, Qingyi; Gu, Cheng-Yuan; Li, Qiao-Xin; Zhu, Yao; Wang, Meng-Yun; Shi, Ting-Yan; Yang, Ya-Yun; ... (10 authors) (Asian journal of andrology, 2014-11)
    Adiponectin secreted by adipose tissue has been implicated in prostate carcinogenesis. Genetic variations in ADIPOQ are thought to influence the activity of adiponectin, thus relating to cancer occurrence. In this hospital-based ...
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    Potentially functional polymorphisms in the ERCC2 gene and risk of esophageal squamous cell carcinoma in Chinese populations. 

    Wei, Qingyi; Zhu, Mei-Ling; He, Jing; Wang, MengYun; Sun, Meng-Hong; Jin, Li; Wang, Xiaofeng; ... (11 authors) (Scientific reports, 2014-01)
    ERCC2 is indispensable for nucleotide excision repair pathway, and its functional polymorphisms may be associated with cancer risk. In a large case-control study of 1126 esophageal squamous cell carcinomas (ESCC) patients ...
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    Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations. 

    Wei, Qingyi; Zhu, Jinhong; Wang, Mengyun; Zhu, Meiling; He, Jin; Wang, Jiu-Cun; Jin, Li; ... (9 authors) (Scientific reports, 2015-01)
    Single nucleotide polymorphisms (SNPs) in the PI3K/PTEN/AKT/mTOR signaling pathway may contribute to carcinogenesis. We genotyped five potentially functional PIK3R1 and mTOR SNPs in 1116 esophageal squamous cell cancer (ESCC) ...
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    Association between single nucleotide polymorphisms in ERCC4 and risk of squamous cell carcinoma of the head and neck. 

    Liu, Zhensheng; Wei, Qingyi; Yu, Hongping; Huang, Yu-Jing; Yin, Ming; Wang, Li-E (PloS one, 2012-01)
    Excision repair cross-complementation group 4 gene (ERCC4/XPF) plays an important role in nucleotide excision repair and participates in removal of DNA interstrand cross-links and DNA double-strand breaks. Single nucleotide ...
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    The miR-184 binding-site rs8126 T>C polymorphism in TNFAIP2 is associated with risk of gastric cancer. 

    Liu, Zhensheng; Wei, Qingyi; Xu, Yu; Ma, Hongxia; Yu, Hongping; Wang, Li-E; Tan, Dongfeng; ... (11 authors) (PloS one, 2013-01)
    TNFAIP2 is a crucial gene involved in apoptosis. Single nucleotide polymorphisms (SNPs) in its miRNA binding sites could modulate functions of the miRNA-target genes and thus risk of cancers. In this study, we investigated ...
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    Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 

    Liu, Zhensheng; Wei, Qingyi; Ma, Hongxia; Wang, Li-E; Sturgis, Erich M (BMC cancer, 2011-06-20)
    Phospholipase C epsilon 1 (PLCE1) (an effector of Ras) belonging to the phospholipase family plays crucial roles in carcinogenesis and progression of several cancers, including squamous cell carcinoma of the head and neck ...
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    Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival. 

    George, Daniel; Moorman, Patricia; Hyslop, Terry; Wei, Qingyi; Patierno, Steven; Freedman, Jennifer; Wang, Yanru; ... (10 authors) (Carcinogenesis, 2018-07)
    Prostate cancer (PCa) is a clinically and molecularly heterogeneous disease, with variation in outcomes only partially predicted by grade and stage. Additional tools to distinguish indolent from aggressive disease are needed. ...
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    Polymorphisms in the mTOR gene and risk of sporadic prostate cancer in an Eastern Chinese population. 

    Wei, Qingyi; Li, Qiaoxin; Gu, Chengyuan; Zhu, Yao; Wang, Mengyun; Yang, Yajun; Wang, Jiucun; ... (13 authors) (PloS one, 2013-01)
    BACKGROUND: The mTOR gene regulates cell growth by controlling mRNA translation, ribosome biogenesis, autophagy, and metabolism. Abnormally increased expression of mTOR was associated with carcinogenesis, and its functional ...
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    A functional NQO1 609C>T polymorphism and risk of gastrointestinal cancers: a meta-analysis. 

    Wei, Qingyi; Yu, Hongping; Liu, Hongliang; Wang, Li-E (PloS one, 2012-01-17)
    The functional polymorphism (rs1800566) in the NQO1 gene, a 609C>T substitution, leading to proline-to-serine amino-acid and enzyme activity changes, has been implicated in cancer risk, but individually published studies ...
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    AuthorWei, Qingyi (41)Jin, Li (15)He, Jing (14)Wang, Meng-Yun (12)Sun, Meng-Hong (11)Wang, Jiu-Cun (11)Yang, Ya-Jun (9)Li, Jin (8)Zhu, Mei-Ling (8)Liu, Hongliang (7)... View MoreDate Issued2012 (8)2013 (8)2016 (8)2018 (5)2011 (3)2014 (3)2015 (3)2009 (1)2017 (1)2019 (1)TypeJournal article (41)Subject
    Genetic Predisposition to Disease (41)
    Humans (41)
    Polymorphism, Single Nucleotide (41)
    Male (34)Middle Aged (34)Female (32)Aged (24)Case-Control Studies (23)Genotype (23)Adult (21)... View MoreAffiliation of Duke Author(s)Basic Science Departments (41)Clinical Science Departments (41)Duke (41)Duke Cancer Institute (41)Institutes and Centers (41)
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    Medicine, Medical Oncology (41)Population Health Sciences (41)School of Medicine (41)Staff (6)... View More