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Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Effects of task instruction on autobiographical memory specificity in young and older adults.
(Memory, 2014)
Older adults tend to retrieve autobiographical information that is overly general
(i.e., not restricted to a single event, termed the overgenerality effect) relative
to young adults' specific memories. A vast majority of ...
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.
(BMC Genomics, 2015-01-22)
BACKGROUND: Expression quantitative trait loci (eQTL) play an important role in the
regulation of gene expression. Gene expression levels and eQTLs are expected to vary
from tissue to tissue, and therefore multi-tissue analyses ...
Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
(Ann Neurol, 2015-04)
OBJECTIVE: A study was undertaken to determine whether better cognitive functioning
at midlife among more physically fit individuals reflects neuroprotection, by which
fitness protects against age-related cognitive decline, ...
A neural biomarker of psychological vulnerability to future life stress.
(Neuron, 2015-02-04)
We all experience a host of common life stressors such as the death of a family member,
medical illness, and financial uncertainty. While most of us are resilient to such
stressors, continuing to function normally, for a ...
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
(Am J Respir Crit Care Med, 2014-08-15)
RATIONALE: Asthma is prospectively associated with age-related chronic diseases and
mortality, suggesting the hypothesis that asthma may relate to a general, multisystem
phenotype of accelerated aging. OBJECTIVES: To test ...
How common are common mental disorders? Evidence that lifetime prevalence rates are doubled by prospective versus retrospective ascertainment.
(Psychol Med, 2010-06)
BACKGROUND: Most information about the lifetime prevalence of mental disorders comes
from retrospective surveys, but how much these surveys have undercounted due to recall
failure is unknown. We compared results ...
An experience-sampling study of depressive symptoms and their social context.
(J Nerv Ment Dis, 2011-06)
Both clinical and subclinical depression are associated with social impairment; however,
few studies have examined the impact of social contact in the daily lives of people
with depressive symptoms. The current study used ...
Remembering from any angle: the flexibility of visual perspective during retrieval.
(Conscious Cogn, 2011-09)
When recalling autobiographical memories, individuals often experience visual images
associated with the event. These images can be constructed from two different perspectives:
first person, in which the event is visualized ...
Adult age differences in functional connectivity during executive control.
(Neuroimage, 2010-08-15)
Task switching requires executive control processes that undergo age-related decline.
Previous neuroimaging studies have identified age-related differences in brain activation
associated with global switching effects (dual-task ...