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A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.
(Psychiatry Res, 2013-04-30)
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk
for suicidality, depression, and functional impairment. We thus conducted a small
(N=12) pilot randomized controlled trial (RCT) with paroxetine ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans,
many of whom continue to experience persistent pain symptoms despite multiple pharmacological
interventions. Preclinical data suggest ...
The frequency of involuntary autobiographical memories and future thoughts in relation to daydreaming, emotional distress, and age.
(Conscious Cogn, 2015-11)
We introduce a new scale, the Involuntary Autobiographical Memory Inventory (IAMI),
for measuring the frequency of involuntary autobiographical memories and involuntary
future thoughts. Using the scale in relation to other ...
Participant, rater, and computer measures of coherence in posttraumatic stress disorder.
(J Abnorm Psychol, 2016-01)
We examined the coherence of trauma memories in a trauma-exposed community sample
of 30 adults with and 30 without posttraumatic stress disorder. The groups had similar
categories of traumas and were matched on multiple ...
Neural correlates of emotional processing in depression: changes with cognitive behavioral therapy and predictors of treatment response.
(J Psychiatr Res, 2011-05)
Major depressive disorder (MDD) is characterized by the presence of disturbances in
emotional processing. However, the neural correlates of these alterations, and how
they may be affected by therapeutic interventions, remain ...
The architecture of cross-hemispheric communication in the aging brain: linking behavior to functional and structural connectivity.
(Cereb Cortex, 2012-01)
Contralateral recruitment remains a controversial phenomenon in both the clinical
and normative populations. To investigate the neural correlates of this phenomenon,
we explored the tendency for older adults to recruit prefrontal ...
Adult age differences in functional connectivity during executive control.
(Neuroimage, 2010-08-15)
Task switching requires executive control processes that undergo age-related decline.
Previous neuroimaging studies have identified age-related differences in brain activation
associated with global switching effects (dual-task ...
Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.
(Arch Gen Psychiatry, 2012-11)
CONTEXT: Smaller hippocampal volumes are well established in posttraumatic stress
disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced
equivocal results. OBJECTIVE: To assess a large cohort ...
Sources of disconnection in neurocognitive aging: cerebral white-matter integrity, resting-state functional connectivity, and white-matter hyperintensity volume.
(Neurobiol Aging, 2017-06)
Age-related decline in fluid cognition can be characterized as a disconnection among
specific brain structures, leading to a decline in functional efficiency. The potential
sources of disconnection, however, are unclear. ...