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A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans.
(Psychiatry Res, 2013-04-30)
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk
for suicidality, depression, and functional impairment. We thus conducted a small
(N=12) pilot randomized controlled trial (RCT) with paroxetine ...
Implementation and randomized controlled trial evaluation of universal postnatal nurse home visiting.
(Am J Public Health, 2014-02)
OBJECTIVES: We evaluated whether a brief, universal, postnatal nurse home-visiting
intervention can be implemented with high penetration and fidelity, prevent emergency
health care services, and promote positive parenting ...
Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan.
(Hum Brain Mapp, 2014-06)
As indicated by several recent studies, magnetic susceptibility of the brain is influenced
mainly by myelin in the white matter and by iron deposits in the deep nuclei. Myelination
and iron deposition in the brain evolve ...
What Do North American Babies Hear? A large-scale cross-corpus analysis.
(Developmental science, 2019-01)
A range of demographic variables influences how much speech young children hear. However,
because studies have used vastly different sampling methods, quantitative comparison
of interlocking demographic effects has been ...
Differences in the cognitive skills of bonobos and chimpanzees.
(PLoS One, 2010-08-27)
While bonobos and chimpanzees are both genetically and behaviorally very similar,
they also differ in significant ways. Bonobos are more cautious and socially tolerant
while chimpanzees are more dependent on extractive foraging, ...
Effects of task instruction on autobiographical memory specificity in young and older adults.
(Memory, 2014)
Older adults tend to retrieve autobiographical information that is overly general
(i.e., not restricted to a single event, termed the overgenerality effect) relative
to young adults' specific memories. A vast majority of ...
Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.
(Transl Psychiatry, 2015-12-15)
Fear conditioning is an established model for investigating posttraumatic stress disorder
(PTSD). However, symptom triggers may vaguely resemble the initial traumatic event,
differing on a variety of sensory and affective ...
Joint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation.
(BMC Genomics, 2015-01-22)
BACKGROUND: Expression quantitative trait loci (eQTL) play an important role in the
regulation of gene expression. Gene expression levels and eQTLs are expected to vary
from tissue to tissue, and therefore multi-tissue analyses ...
Cardiorespiratory fitness and cognitive function in midlife: neuroprotection or neuroselection?
(Ann Neurol, 2015-04)
OBJECTIVE: A study was undertaken to determine whether better cognitive functioning
at midlife among more physically fit individuals reflects neuroprotection, by which
fitness protects against age-related cognitive decline, ...
A neural biomarker of psychological vulnerability to future life stress.
(Neuron, 2015-02-04)
We all experience a host of common life stressors such as the death of a family member,
medical illness, and financial uncertainty. While most of us are resilient to such
stressors, continuing to function normally, for a ...