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Moving Beyond Program to Population Impact: Toward a Universal Early Childhood System of Care
(Journal of Family Theory and Review, 2018-01-01)
© 2018 National Council on Family Relations Families have clearly benefited from increased
availability of evidence-based intervention, including home-visiting models and increased
federal funding for programs benefiting ...
Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration.
(Nature communications, 2018-04-30)
Inherited retinal degenerations, affecting more than 2 million people worldwide, are
caused by mutations in over 200 genes. This suggests that the most efficient therapeutic
strategies would be mutation independent, i.e., ...
Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors.
(eNeuro, 2018-05)
The heterotrimeric G-protein transducin mediates visual signaling in vertebrate photoreceptor
cells. Many aspects of the function of transducin were learned from knock-out mice
lacking its individual subunits. Of particular ...
Using Early Childhood Behavior Problems to Predict Adult Convictions.
(Journal of abnormal child psychology, 2018-10-03)
The current study examined whether teacher and parent ratings of externalizing behavior
during kindergarten and 1st grade accurately predicted the presence of adult convictions
by age 25. Data were collected as part of the ...
Perspectives on genetic and genomic technologies in an academic medical center: the duke experience.
(Journal of personalized medicine, 2015-04-03)
In this age of personalized medicine, genetic and genomic testing is expected to become
instrumental in health care delivery, but little is known about its actual implementation
in clinical practice.We surveyed Duke faculty ...
The Emergency Department as an Opportunity for Naloxone Distribution.
(The western journal of emergency medicine, 2018-11)
Introduction:Substance use disorders, including opioid use disorders, are a major
public health concern in the United States. Between 2005 and 2014, the rate of opioid-related
emergency department (ED) visits nearly doubled, ...
Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms.
(Nicotine & tobacco research : official journal of the Society for Research on Nicotine
and Tobacco, 2018-12-24)
Introduction:Both prenatal smoke exposure and depression have been linked to lower
birth weight, a risk factor for morbidity and mortality. Few studies have looked at
the interaction between these risk factors and none have ...
The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.
(Journal of the American Geriatrics Society, 2019-01-23)
BACKGROUND/OBJECTIVES:Every year, up to 40% of the more than 16 million older Americans
who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD)
or delirium. Each of these distinct syndromes is associated ...
Validation of the Sleep Regularity Index in Older Adults and Associations with Cardiometabolic Risk.
(Scientific reports, 2018-09-21)
Sleep disturbances, including insufficient sleep duration and circadian misalignment,
confer risk for cardiometabolic disease. Less is known about the association between
the regularity of sleep/wake schedules and cardiometabolic ...
Pre-Pregnancy Weight and Symptoms of Attention Deficit Hyperactivity Disorder and Executive Functioning Behaviors in Preschool Children.
(International journal of environmental research and public health, 2019-02-25)
This study examines pre-pregnancy Body Mass Index (BMI) and gestational weight gain
(GWG) in relation to early childhood Attention Deficit Hyperactivity Disorder (ADHD)
symptoms and related executive self-regulation behaviors. ...