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A pri-miR-218 variant and risk of cervical carcinoma in Chinese women. 

Shi, Ting-Yan; Chen, Xiao-Jun; Zhu, Mei-Ling; Wang, Meng-Yun; He, Jing; Yu, Ke-Da; Shao, Zhi-Ming; ... (12 authors) (BMC cancer, 2013-01-15)
BACKGROUND: MicroRNA (miRNA)-related single nucleotide polymorphisms (SNPs) may compromise miRNA binding affinity and modify mRNA expression levels of the target genes, thus leading to cancer susceptibility. However, few ...
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Polymorphisms of nucleotide excision repair genes predict melanoma survival. 

Li, Chunying; Yin, Ming; Wang, Li-E; Amos, Christopher I; Zhu, Dakai; Lee, Jeffrey E; Gershenwald, Jeffrey E; ... (9 authors) (The Journal of investigative dermatology, 2013-07)
Melanoma is the most highly malignant skin cancer, and nucleotide excision repair (NER) is involved in melanoma susceptibility. In this analysis of 1,042 melanoma patients, we evaluated whether genetic variants of NER genes ...
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Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy. 

Yin, Ming; Liao, Zhongxing; Huang, Yu-Jing; Liu, Zhensheng; Yuan, Xianglin; Gomez, Daniel; Wang, Li-E; ... (8 authors) (PloS one, 2011-01)
The repair of DNA double-strand breaks (DSBs) is the major mechanism to maintain genomic stability in response to irradiation. We hypothesized that genetic polymorphisms in DSB repair genes may affect clinical outcomes among ...
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Pri-miR-124 rs531564 and pri-miR-34b/c rs4938723 polymorphisms are associated with decreased risk of esophageal squamous cell carcinoma in Chinese populations. 

Zhang, Junjie; Huang, Xuewen; Xiao, Juanjuan; Yang, Yajun; Zhou, Yinghui; Wang, Xiaofeng; Liu, Qingmei; ... (18 authors) (PloS one, 2014-01)
MicroRNAs are a new class of small non-protein-coding RNAs that sometimes function as tumor suppressors or oncogenes. Aberrant expression and structural alteration of microRNAs have been reported to be involved in tumorigenesis ...
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Genotypes and haplotypes of the VEGF gene and survival in locally advanced non-small cell lung cancer patients treated with chemoradiotherapy. 

Guan, Xiaoxiang; Yin, Ming; Wei, Qingyi; Zhao, Hui; Liu, Zhensheng; Wang, Li-E; Yuan, Xianglin; ... (10 authors) (BMC cancer, 2010-08-16)
Vascular endothelial growth factor (VEGF) is a major mediator of angiogenesis involving in carcinogenesis, including lung cancer. We hypothesized that VEGF polymorphisms may affect survival outcomes among locally advanced ...
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Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer. 

Han, Chan H; Huang, Yu-Jing; Lu, Karen H; Liu, Zhensheng; Mills, Gordon B; Wei, Qingyi; Wang, Li-E (Journal of experimental & clinical cancer research : CR, 2011-01-07)
SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ...
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Functional variant of MTOR rs2536 and survival of Chinese gastric cancer patients. 

Cheng, Lei; Qiu, Lixin; Zhang, Ruoxin; Qian, Danwen; Wang, Mengyun; Sun, Menghong; Zhu, Xiaodong; ... (10 authors) (International journal of cancer, 2019-01)
We previously reported that some single nucleotide polymorphisms (SNPs) of candidate genes involved in the MTOR complex1 (MTORC1) were associated with risk of gastric cancer (GCa). In the present study, we further evaluated ...
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Genetic variant of IRAK2 in the toll-like receptor signaling pathway and survival of non-small cell lung cancer. 

Xu, Yinghui; Liu, Hongliang; Liu, Shun; Wang, Yanru; Xie, Jichun; Stinchcombe, Thomas E; Su, Li; ... (11 authors) (International journal of cancer, 2018-11)
The toll-like receptor (TLR) signaling pathway plays an important role in the innate immune responses and antigen-specific acquired immunity. Aberrant activation of the TLR pathway has a significant impact on carcinogenesis ...
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Association of tumor necrosis factor-alpha promoter variants with risk of HPV-associated oral squamous cell carcinoma. 

Jin, Lei; Sturgis, Erich M; Zhang, Yang; Huang, Zhigang; Song, Xicheng; Li, Chao; Wei, Qingyi; ... (8 authors) (Molecular cancer, 2013-07-19)
Tumor necrosis factor alpha (TNF-α) plays an important role in inflammation, immunity, and defense against infection and clearance of human papillomavirus (HPV). Thus, genetic variants may modulate individual susceptibility ...
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TGFβ1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy. 

Yuan, Xianglin; Wei, Qingyi; Komaki, Ritsuko; Liu, Zhensheng; Yang, Ju; Tucker, Susan L; Xu, Ting; ... (11 authors) (PloS one, 2013-01)
Transforming growth factor (TGF) -β1 signaling is involved in cancer-cell metastasis. We investigated whether single nucleotide polymorphisms (SNPs) at TGFβ1 were associated with overall survival (OS) and distant metastasis-free ...
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Wei, Qingyi (58)
Liu, Hongliang (15)Liu, Zhensheng (15)Wang, Li-E (15)Amos, Christopher I (11)Sturgis, Erich M (11)Lee, Jeffrey E (10)Wang, Mengyun (10)Li, Guojun (9)Fang, Shenying (8)... View MoreDate Issued2012 (11)2018 (10)2013 (9)2015 (9)2011 (6)2016 (6)2017 (2)2019 (2)2009 (1)2010 (1)TypeJournal article (58)Subject
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Polymorphism, Single Nucleotide (58)
Middle Aged (48)Female (47)Male (44)Aged (37)Genetic Predisposition to Disease (33)Genotype (31)Adult (30)Case-Control Studies (22)... View MoreAffiliation of Duke Author(s)Clinical Science Departments (58)Duke (58)Duke Cancer Institute (58)Institutes and Centers (58)
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