Now showing items 31-40 of 245
Improvement in visual search with practice: mapping learning-related changes in neurocognitive stages of processing.
(J Neurosci, 2015-04-01)
Practice can improve performance on visual search tasks; the neural mechanisms underlying such improvements, however, are not clear. Response time typically shortens with practice, but which components of the stimulus-response ...
Trauma re-experiencing symptoms modulate topology of intrinsic functional networks.
(Biol Psychiatry, 2015-08-01)
Survey of methadone-drug interactions among patients of methadone maintenance treatment program in Taiwan.
(Subst Abuse Treat Prev Policy, 2012-03-20)
BACKGROUND: Although methadone has been used for the maintenance treatment of opioid dependence for decades, it was not introduced in China or Taiwan until 2000s. Methadone-drug interactions (MDIs) have been shown to cause ...
Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD.
(J Psychiatr Res, 2011-05)
Neurobiological models of posttraumatic stress disorder (PTSD) suggest that altered activity in the medial temporal lobes (MTL) during encoding of traumatic memories contribute to the development and maintenance of the disorder. ...
Prefrontal contributions to relational encoding in amnestic mild cognitive impairment.
(Neuroimage Clin, 2016)
Relational memory declines are well documented as an early marker for amnestic mild cognitive impairment (aMCI). Episodic memory formation relies on relational processing supported by two mnemonic mechanisms, generation ...
Sources of disconnection in neurocognitive aging: cerebral white-matter integrity, resting-state functional connectivity, and white-matter hyperintensity volume.
(Neurobiol Aging, 2017-06)
Age-related decline in fluid cognition can be characterized as a disconnection among specific brain structures, leading to a decline in functional efficiency. The potential sources of disconnection, however, are unclear. ...
Cortical Brain Activity Reflecting Attentional Biasing Toward Reward-Predicting Cues Covaries with Economic Decision-Making Performance.
(Cereb Cortex, 2016-01)
Adaptive choice behavior depends critically on identifying and learning from outcome-predicting cues. We hypothesized that attention may be preferentially directed toward certain outcome-predicting cues. We studied this ...
The influence of different Stop-signal response time estimation procedures on behavior-behavior and brain-behavior correlations.
(Behav Brain Res, 2012-04-01)
The fundamental cognitive-control function of inhibitory control over motor behavior has been extensively investigated using the Stop-signal task. The critical behavioral parameter describing stopping efficacy is the Stop-signal ...
Less wiring, more firing: low-performing older adults compensate for impaired white matter with greater neural activity.
(Cereb Cortex, 2015-04)
The reliable neuroimaging finding that older adults often show greater activity (over-recruitment) than younger adults is typically attributed to compensation. Yet, the neural mechanisms of over-recruitment in older adults ...
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)
BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest ...